301191-47-9

Basic information

• Product Name: N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]formamide
• Synonyms: N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]formamide
• CAS NO: 301191-47-9
• Molecular Weight: 241.29
• Mol File: 301191-47-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]formamide(301191-47-9)
• EPA Substance Registry System: N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]formamide(301191-47-9)

Safety Data

• Hazardous Substances Data: 301191-47-9(Hazardous Substances Data)

Upstream product

• 530-36-9 (1S,2S)-2-amino-1,2-diphenylethanol 
• 77287-34-4 formamide 
• 109-94-4 formic acid ethyl ester 
• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 
• 39664-88-5 N-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]formamide 
• 2258-42-6 formyl acetic anhydride 
• 64-18-6 formic acid 

Downstream Products

• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 
• 550-58-3 (1R,2S)-1,2-diphenyl-2-(N-methyl)aminoethanol 
• 1380325-25-6 N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N-methylbutyramide 
• 1380325-26-7 N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N-methylmethacrylamide 
• 1380325-27-8 N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N-methyl-3-phenylpropanamide 
• 1380325-28-9 N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N-methylhexanamide 
• 1380325-29-0 N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N-methyl-2-methylenebutanamide 
• 1380325-31-4 (R)-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2-dimethyl-3-phenylpropanamide 
• 1380325-33-6 CF₃O₃S^(1-)*C₂₅H₂₆NO⁽¹⁺⁾ 
• 1380325-34-7 (R)-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2-dimethylhexanamide 
• 1380325-35-8 (R)-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2-dimethylbutanamide 
• 1380325-36-9 (S)-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2-dimethylbutanamide 
• 1380325-37-0 (R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N-methylhexanamide 
• 1380325-38-1 (S)-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2-dimethylhexanamide 

Relevant articles and documents

Stereoinversion of Unactivated Alcohols by Tethered Sulfonamides

The direct, catalytic substitution of unactivated alcohols remains an undeveloped area of organic synthesis. Moreover, catalytic activation of this difficult electrophile with predictable stereo-outcomes presents an even more formidable challenge. Described herein is a simple iron-based catalyst system which provides the mild, direct conversion of secondary and tertiary alcohols to sulfonamides. Starting from enantioenriched alcohols, the intramolecular variant proceeds with stereoinversion to produce enantioenriched 2- and 2,2-subsituted pyrrolidines and indolines, without prior derivatization of the alcohol or solvolytic conditions.

Aminophosphine phosphinites derived from chiral 1,2-diphenyl-2-aminoethanols: Synthesis and application in rhodium-catalyzed asymmetric hydrogenation of dehydroamino acid derivatives

A series of chiral aminophosphine phosphinites DPAMPPs was synthesized from optically active 1,2-diphenyl-2-aminoethanols. The erythro-DPAMPPs were found to serve as excellent ligands for rhodium-catalyzed asymmetric hydrogenation of dehydroamino acid derivatives. For an array of dehydroamino acid precursors, remarkably high enantioselectivity (up to 98.4% e.e.) and reactivity (the ratio of substrate/catalyst up to 10000) were observed. Some factors controlling the enantioselectivity were examined and discussed. (C) 2000 Elsevier Science Ltd.