39664-88-5

Basic information

• Product Name: N-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]formamide
• Synonyms: N-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]formamide
• CAS NO: 39664-88-5
• Molecular Weight: 241.29
• Mol File: 39664-88-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]formamide(39664-88-5)
• EPA Substance Registry System: N-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]formamide(39664-88-5)

Safety Data

• Hazardous Substances Data: 39664-88-5(Hazardous Substances Data)

Upstream product

• 14149-03-2 (1R,2S)-(-)-2-Amino-1,2-diphenyl-1-ethanol hydrochloride 
• 77287-34-4 formamide 
• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 
• 109-94-4 formic acid ethyl ester 
• 301191-47-9 N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]formamide 
• 50-00-0 formaldehyd 
• 530-36-9 threo-1,2-diphenyl-2-aminoethan-1-ol 
• 530-36-9 (1S,2S)-2-amino-1,2-diphenylethanol 

Downstream Products

• 550-58-3 (1R,2S)-1,2-diphenyl-2-(N-methyl)aminoethanol 
• 1380325-24-5 (S,S)-N-(2-hydroxy-1,2-diphenylethyl)-N-methylpropionamide 
• 1380325-71-2 CF₃O₃S^(1-)*C₂₈H₄₀NO⁽¹⁺⁾ 
• 1380325-69-8 (R)-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2-dimethyl-2-neopentylheptanamide 
• 1380325-68-7 CF₃O₃S^(1-)*C₂₅H₃₄NO⁽¹⁺⁾ 
• 1380325-66-5 (R)-2-ethyl-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2,4,4-tetramethylpentanamide 
• 1380325-65-4 CF₃O₃S^(1-)*C₂₆H₃₄NO⁽¹⁺⁾ 
• 1380325-63-2 (S)-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2-dimethyl-2-neopentylpent-4-enamide 
• 1380325-62-1 CF₃O₃S^(1-)*C₂₆H₃₄NO⁽¹⁺⁾ 
• 1380325-60-9 (R)-2-allyl-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2-dimethylheptanamide 
• 1380325-59-6 CF₃O₃S^(1-)*C₃₀H₃₆NO⁽¹⁺⁾ 
• 1380325-57-4 (R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2-dimethylheptanamide 
• 1380325-55-2 CF₃O₃S^(1-)*C₂₈H₃₀NO⁽¹⁺⁾ 
• 1380325-53-0 (S)-2-benzyl-N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N,2-dimethylpent-4-enamide 

Relevant articles and documents

Aminophosphine phosphinites derived from chiral 1,2-diphenyl-2-aminoethanols: Synthesis and application in rhodium-catalyzed asymmetric hydrogenation of dehydroamino acid derivatives

A series of chiral aminophosphine phosphinites DPAMPPs was synthesized from optically active 1,2-diphenyl-2-aminoethanols. The erythro-DPAMPPs were found to serve as excellent ligands for rhodium-catalyzed asymmetric hydrogenation of dehydroamino acid derivatives. For an array of dehydroamino acid precursors, remarkably high enantioselectivity (up to 98.4% e.e.) and reactivity (the ratio of substrate/catalyst up to 10000) were observed. Some factors controlling the enantioselectivity were examined and discussed. (C) 2000 Elsevier Science Ltd.

Enzyme-Catalyzed Reactions, 8. - Stereoselective Synthesis of 2-Amino Alcohols from (R)- and (S)-Cyanohydrins

erythro-2-Amino alcohols (1R,2S)- and (1S,2R)-4 may be synthesized stereoselectively by addition of Grignard compounds to cyanohydrins (R)-, (S)-1 and their O-trimethylsilyl derivatives 3, respectively, followed by hydrogenation.The threo-2-amino alcohols (1S,2S)- and (1R,2R)-4 are easily accessible by inversion at C-1 of the (1R,2S) and (1S,2R) compounds.