303048-98-8

Basic information

• Product Name: 2?[(2RS)?2?(1?chlorocyclopropyl)?3?(2?chlorophenyl)?2?hydroxypropyl]?2H?1,2,4?triazole?3(4H)?thione
• CAS NO: 303048-98-8
• Molecular Weight: 344.265
• Mol File: 303048-98-8.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: 2?[(2RS)?2?(1?chlorocyclopropyl)?3?(2?chlorophenyl)?2?hydroxypropyl]?2H?1,2,4?triazole?3(4H)?thione(CAS DataBase Reference)
• NIST Chemistry Reference: 2?[(2RS)?2?(1?chlorocyclopropyl)?3?(2?chlorophenyl)?2?hydroxypropyl]?2H?1,2,4?triazole?3(4H)?thione(303048-98-8)
• EPA Substance Registry System: 2?[(2RS)?2?(1?chlorocyclopropyl)?3?(2?chlorophenyl)?2?hydroxypropyl]?2H?1,2,4?triazole?3(4H)?thione(303048-98-8)

Safety Data

• Hazardous Substances Data: 303048-98-8(Hazardous Substances Data)

Usage

Functional Groups

Triazole ring: Provides potential antifungal or antibacterial properties.
Thione group: Also contributes to potential antifungal or antibacterial activity.
Chlorocyclopropyl group: Indicates potential insecticidal or pesticidal properties.
Chlorophenyl group: Suggests additional insecticidal or pesticidal activity.
Hydroxypropyl group: Indicates potential water solubility, enhancing its applicability in various formulations.

Potential Biological Activities

Antifungal: Due to the presence of triazole and thione groups.
Antibacterial: Also attributed to the triazole and thione functional groups.
Insecticidal/Pesticidal: Suggested by the chlorocyclopropyl and chlorophenyl groups.

Applicability

Pharmaceutical: Potential as an antifungal or antibacterial agent.
Agricultural: Possible use as an insecticide or pesticide.
Industrial: Could be utilized in formulations requiring water solubility or biological activity.

Upstream product

• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 
• 2444-36-2 2'-chloro-benzeneacetic acid 
• 51512-09-5 2-(2-chlorophenyl)acetyl chloride 
• 946402-82-0 2-(2-chlorophenyl)-N-methoxy-N-methylacetamide 
• 139297-65-7 1-(1-chlorocyclopropyl)-2-(2-chlorophenyl)ethanone 
• 540-72-7 sodium thiocyanide 
• 222408-91-5 [2-(1-chloro-cycloprop-1-yl)-3-(2-chlorophenyl)-2-hydroxy]-propyl-1-hydrazine 
• 298-12-4 Glyoxilic acid 
• 1147550-11-5 ammonium thiocyanate 
• 222408-90-4 [2-(1-chlorocyclopropyl-1-yl)-1-(2-chlorophenyl)-2-hydroxy-3-propane]-(1,2,4-triazolidine-3-thiol-1-yl) 
• 7783-06-4 hydrogen sulfide 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 2290-65-5 trimethylsilyl isothiocyanate 

Downstream Products

• 199391-98-5 di-{1-[2-(1-chlorocyclopropyl)-3-(2-chloro-phenyl)-2-hydroxy-propyl-1]-1,2,4-triazol-5-yl} disulphide 
• 199105-36-7 sodium salt of 2-(1-chloro-cyclopropyl)-1-(2-chlorophenyl)-3-(5-mercapto-1,2,4-triazol-1-yl)-propan-2-ol 
• 199851-46-2 2-(1-chloro-cyclopropyl)-1-(2-chloro-phenyl)-3-(4-methanesulphonyl-5-thiono-4,5-dihydro-1,2,4-triazol-1-yl)-propan-2-ol 

Relevant articles and documents

AN INDUSTRIAL SCALE PROCESS FOR THE PREPARATION OF PROTHIOCONAZOLE

The present invention relates to an industrial scale process for the preparation of Prothioconazole (I), which is simple, economical, efficient, user and environment friendly, moreover commercially viable with higher yield and greater chemical purity.

Preparation method of prothioconazole compound

The invention relates to the field of bactericides, and discloses a preparation method of a prothioconazole compound. The method comprises the steps of 1) reacting a compound with a structure as shown in a formula (1) defined in the description with hydra