304649-69-2Relevant articles and documents
Pharmacophoric 2-hydroxyalkyl benzenesulfonamide: A single-step synthesis from benzenesulfonamide via hemiaminal
Singh, Sunil K.,Shivaramakrishna,Saibaba,Rao, K. Srinivas,Ganesh, K. Ravi,Vasudev,Kumar, P. Praveen,Babu, J. Moses,Vyas,Rao, Y. Koteswar,Iqbal
, p. 456 - 462 (2008/02/07)
ortho-Acylation attempt of benzenesulfonamide afforded the corresponding hemiaminal as major product. The in situ reduction of the reaction mixture, reported herein, directly provided 2-hydroxyalkyl benzenesulfonamide, an important pharmacophoric element