29083-05-4

Basic information

• Product Name: N-tert-Butyl-4-fluorobenzenesulfonamide
• Synonyms: N-tert-Butyl-4-fluorobenzenesulfonamide
• CAS NO: 29083-05-4
• Molecular Formula: C₁₀H₁₄FNO₂S
• Molecular Weight: 231.2870632
• Mol File: 29083-05-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-tert-Butyl-4-fluorobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-Butyl-4-fluorobenzenesulfonamide(29083-05-4)
• EPA Substance Registry System: N-tert-Butyl-4-fluorobenzenesulfonamide(29083-05-4)

Safety Data

• Hazardous Substances Data: 29083-05-4(Hazardous Substances Data)

Usage

General Description

N-tert-Butyl-4-fluorobenzenesulfonamide is an organic compound that belongs to the class of sulfonamides. It is composed of a tert-butyl group attached to a 4-fluorobenzenesulfonamide moiety. This chemical is commonly used as a reagent in organic synthesis, particularly in the preparation of various pharmaceutical compounds. N-tert-Butyl-4-fluorobenzenesulfonamide is also known for its ability to act as a mild base, and it has been utilized in the synthesis of various heterocyclic compounds. Additionally, it has shown potential as an intermediate in the synthesis of agrochemicals and dyes. Overall, N-tert-Butyl-4-fluorobenzenesulfonamide is a versatile compound with various synthetic applications.

Upstream product

• 349-88-2 4-Fluorobenzenesulfonyl chloride 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 
• 75-64-9 tert-butylamine 
• 402-46-0 4-fluorophenylsulphonamide 
• 84379-72-6 1,3-dioxoisoindolin-2-yl 3,3-dimethylbutanoate 

Downstream Products

• 402-46-0 4-fluorophenylsulphonamide 
• 304649-53-4 N-tert-butyl-4-fluoro-2-hydroxymethylbenzenesulfonamide 
• 304649-57-8 4-fluoro-2-hydroxymethyl-1-benzenesulfonamide 
• 304649-69-2 4-hydrazino-2-hydroxymethyl-1-benzenesulfonamide 
• 1418634-79-3 C₁₇H₁₆FNO₄S 

Relevant articles and documents

Organophotoredox-Catalyzed Decarboxylative N-Alkylation of Sulfonamides

We developed an organophotoredox-catalyzed reaction for N-alkylation of sulfonamides with aliphatic carboxylic acid-derived redox active esters as alkylating reagents. Under mild and transition metal-free conditions, a series of functionalized N-alkylated sulfonamides were prepared. This protocol also enabled the functionalization of pharmaceutical drugs bearing a sulfonamide or carboxylic acid moiety. This radical-mediated process allowed the assembly of three components including sulfonamides, redox active esters, and alkenes to yield complex sulfonamides in a one-pot manner.

Copper (II)/RuPHOX-Catalyzed Enantioselective Mannich-Type Reaction of Glycine Schiff Bases with Cyclic Ketimines

A Cu(II)/RuPHOX-catalyzed enantioselective Mannich-type reaction of glycine Schiff bases with cyclic ketimines was developed, affording chiral α,?-diamino acid derivatives in good yields with moderate to good ee and dr values. This provides an efficient methodology for furnishing chiral Cβ-tetrasubstituted α,β-diamino acid precursors. The catalytic system is compatible with a series of substrates. In addition, an interesting nonlinear effect of the catalyst's enantiomeric composition on reaction enantioselectivity was observed. (Figure presented.).

Simple branched sulfur-olefins as chiral ligands for Rh-catalyzed asymmetric arylation of cyclic ketimines: Highly enantioselective construction of tetrasubstituted carbon stereocenters

New, simple, sulfinamide-based branched olefin ligands have been developed and successfully used in Rh-catalyzed asymmetric arylations of cyclic ketimines, providing efficient and highly enantioselective access to valuable benzosultams and benzosulfamidat