30469-82-0

Basic information

• Product Name: (2-Biphenylyl)phenylmethanol
• Synonyms: (2-Biphenylyl)phenylmethanol;Biphenyl-2-yl(phenyl)methanol;α-(2-Biphenylyl)benzyl alcohol;α-Phenyl-1,1'-biphenyl-2-methanol;α-Phenylbiphenyl-2-methanol
• CAS NO: 30469-82-0
• Molecular Formula: C₁₉H₁₆O
• Molecular Weight: 260.32974
• Mol File: 30469-82-0.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-Biphenylyl)phenylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Biphenylyl)phenylmethanol(30469-82-0)
• EPA Substance Registry System: (2-Biphenylyl)phenylmethanol(30469-82-0)

Safety Data

• Hazardous Substances Data: 30469-82-0(Hazardous Substances Data)

Upstream product

• 1985-32-6 2-phenylbenzophenone 
• 100-52-7 benzaldehyde 
• 23533-35-9 biphenyl-2-ylmagnesium iodide 
• 1942-82-1 [1,1′-biphenyl]-2-yldimethylphosphine oxide 
• 30545-62-1 acetic acid (biphenyl-2-yl)(phenyl)methyl ester 
• 2052-07-5 2-Bromobiphenyl 
• 59142-47-1 (2-bromophenyl)phenylmethanol 
• 591-51-5 phenyllithium 
• 1088-00-2 9-phenyl-9-phosphafluorene 
• 1031-13-6 5-phenyl-5H-dibenzophosphole-5-oxide 
• 791-28-6 Triphenylphosphine oxide 
• 108-86-1 bromobenzene 
• 1203-68-5 2-Phenylbenzaldehyde 
• 13029-09-9 2,2'-dibromobiphenyl 

Downstream Products

• 41858-29-1 2-(Biphenyl-2-yl-phenyl-methoxy)-N,N-dimethyl-acetamide 
• 321-60-8 2-fluorobiphenyl 
• 30469-78-4 2-(α-chlorophenylmethyl)biphenyl 
• 789-24-2 9-Phenylfluorene 
• 680198-63-4 2-phenylbenzhydryl bromide 
• 52731-68-7 phenyl-6 phospha-5 phenanthrene 
• 680198-67-8 5,6-dihydro-6-phenyldibenzo[b,d]phosphinine 
• 680198-68-9 5-chloro-5,6-dihydro-6-phenyldibenzo[b,d]phosphinine 
• 680198-66-7 5,6-dihydro-5-hydroxy-5-oxo-6-phenyldibenzo[b,d]phosphinine 
• 680198-65-6 2-phenylbenzhydrylphosphonic acid 
• 680198-64-5 diethyl ([1,1'-biphenyl]-2-yl(phenyl)methyl)phosphonate 
• 41858-63-3 3-Biphenyl-2-yl-2-hydroxy-N,N-dimethyl-3-phenyl-propionamide 
• 30469-83-1 2-(α-methoxyphenylmethyl)biphenyl 
• 1065544-65-1 2,2'-(oxybis(phenylmethylene))dibiphenyl 

Relevant articles and documents

Chiral electron-rich PNP ligand with a phospholane motif: Structural features and application in asymmetric hydrogenation

Despite the remarkable reactivity that was achieved by a series of transition-metal catalysts with a PNP type ligand, the electron-rich chiral PNP ligands have still been rarely reported because of the difficulties in synthesis and the nature of air-sensitivity. Herein, we report a novel chiral PNP ligand (Heng-PNP) with both a rigid backbone and a bulky tert-butyl group on the phospholane motif. We successfully obtained its divalent iron complex. The chiral environment of its Ir(III) complex was also discussed with quadrant analysis. This tridentate ligand was applied in iridium-catalyzed asymmetric hydrogenation of challenging diaryl ketones: up to 98% ee and 500 TON are achieved. Computational study showed that the twist of conjugate aryl group in the substrate (induced by the special chiral pocket of Ir/Heng-PNP complex) leads to the energy difference in the enantiodetermining step.

Solvent control of product diversity in palladium-catalyzed addition of arylboronic acid to aryl aldehydes

In Pd-catalyzed arylboronic acid addition to aryl aldehydes, the expected carbinol or asymmetrical ether can be obtained as the major product by altering aqueous solvent composition. Exploiting this methodology with 2-formylbiphenyls as reaction partner, a fluorene scaffold can be readily constructed in two steps.

Palladium-imidazolinium carbene-catalyzed arylation of aldehydes with arylboronic acids in water

The catalytic arylation of aldehydes with arylboronic acids in only water was found to be achieved using the palladium/thioether-imidazolinium chloride system in good to excellent yields. This catalytic process showed high tolerance for a broad range of substrates, giving a variety of carbinol derivatives with 2.0-3.0 mol % of the catalyst.