304693-64-9 Usage
Description
Ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate is an organic compound that belongs to the class of pyrimidine derivatives. It is characterized by the presence of a trifluoromethyl group and a carboxylate functional group, which contribute to its unique chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
Ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate is used as a key intermediate in the synthesis of NF-κB and AP-1 gene inhibitors. These inhibitors play a crucial role in regulating the expression of genes involved in inflammation, immune response, and cell proliferation. By targeting these transcription factors, Ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate contributes to the development of novel therapeutics for various diseases, including autoimmune disorders, chronic inflammation, and cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 304693-64-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,4,6,9 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 304693-64:
(8*3)+(7*0)+(6*4)+(5*6)+(4*9)+(3*3)+(2*6)+(1*4)=139
139 % 10 = 9
So 304693-64-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H7F3N2O2/c1-2-15-6(14)5-3-12-7(13-4-5)8(9,10)11/h3-4H,2H2,1H3
304693-64-9Relevant articles and documents
P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN
-
Paragraph 0136, (2018/02/04)
The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X3 receptor s
Condensed pyrazole derivative
-
Page/Page column 134, (2016/10/08)
The present invention provides cyclic aminomethylpyrimidine derivatives and pharmaceutically acceptable salts thereof which show high selectivity for dopamine D4 receptors and are useful for treating diseases such as attention deficit hyperacti
P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN
-
Page/Page column 68-69, (2010/11/18)
The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X3 receptor subunit modulator.
