3057-74-7 Usage
Description
L-Aspartic acid 4-tert-butyl ester is a protected form of L-Aspartic acid, which is a nonessential amino acid playing a crucial role in the biosynthesis of other amino acids within the human body. L-Aspartic acid 4-tert-butyl ester is characterized by its white powder appearance and is known to enhance membrane conductance in mammalian neurons through voltage-dependent mechanisms, leading to depolarization and the propagation of nerve impulses to vital regions of the central nervous system.
Uses
Used in Pharmaceutical Industry:
L-Aspartic acid 4-tert-butyl ester is used as an intermediate in the synthesis of various pharmaceutical compounds for its ability to protect the L-Aspartic acid moiety during chemical reactions. This protection is essential for the successful synthesis of complex molecules with specific biological activities.
Used in Neurochemistry Research:
As a modulator of membrane conductance in mammalian neurons, L-Aspartic acid 4-tert-butyl ester is used as a research tool to study the mechanisms underlying neuronal depolarization and nerve impulse transmission. This application aids in understanding the fundamental processes of the central nervous system and can contribute to the development of treatments for neurological disorders.
Used in Amino Acid Biosynthesis:
L-Aspartic acid 4-tert-butyl ester serves as a protected form of L-Aspartic acid, which is used as a building block in the biosynthesis of other amino acids. This makes it an essential component in the production of amino acids required for various biological processes, including protein synthesis and metabolic functions.
Used in Chemical Synthesis:
Due to its protective nature, L-Aspartic acid 4-tert-butyl ester is utilized in chemical synthesis to facilitate the production of complex molecules with specific functionalities. This application is particularly relevant in the development of new drugs, materials, and other specialty chemicals that require the precise incorporation of L-Aspartic acid.
Check Digit Verification of cas no
The CAS Registry Mumber 3057-74-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,0,5 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3057-74:
(6*3)+(5*0)+(4*5)+(3*7)+(2*7)+(1*4)=77
77 % 10 = 7
So 3057-74-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H15NO4/c1-8(2,3)13-6(10)4-5(9)7(11)12/h5H,4,9H2,1-3H3,(H,11,12)/t5-/m1/s1
3057-74-7Relevant articles and documents
Preparation of the beta-tert-butyl ester of L-asparaginic acid.
WUENSCH,ZWICK
, p. 235 - 240 (1962)
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Gold-Catalyzed Amide/Carbamate-Linked N, O-Acetal Formation with Bulky Amides and Alcohols
Ohsawa, Kosuke,Ochiai, Shota,Kubota, Junya,Doi, Takayuki
, p. 1281 - 1291 (2021/01/14)
A gold-catalyzed N,O-acetal formation was established to construct an amide/carbamate-linked N,O-acetal substructure with bulky alcohols. The acyliminium cation species generated from o-alkynylbenzoic acid ester in the presence of a gold catalyst is highly reactive and underwent nucleophilic attack of various bulky alcohols and phenols at room temperature under neutral conditions, leading to the corresponding N,O-acetals in yields of 34-89% with good functional group tolerance.
Reliable and safe, gram-scale hydrogenation and hydrogenolysis of O-benzyl ether groups with in situ Pd0/C catalyst
Felpin, Francois-Xavier,Fouquet, Eric
experimental part, p. 2893 - 2896 (2011/10/13)
Hydrogenation of alkenes, alkynes, and hydrogenolysis of O-benzyl ethers with Pd0/C catalyst generated in situ can be readily scaled up under safer conditions than with traditional procedures. The precise control of the palladium loading and the mild conditions developed allow the formation of a very active and reliable Pd0/C catalyst, leading to highly reproducible results. Georg Thieme Verlag Stuttgart - New York.
