306973-02-4

Basic information

• Product Name: 3-Bromo-4-methoxyphenyl (S)-2-bromodecanoate
• Synonyms: 3-Bromo-4-methoxyphenyl (S)-2-bromodecanoate
• CAS NO: 306973-02-4
• Molecular Weight: 436.184
• Mol File: 306973-02-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Bromo-4-methoxyphenyl (S)-2-bromodecanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-4-methoxyphenyl (S)-2-bromodecanoate(306973-02-4)
• EPA Substance Registry System: 3-Bromo-4-methoxyphenyl (S)-2-bromodecanoate(306973-02-4)

Safety Data

• Hazardous Substances Data: 306973-02-4(Hazardous Substances Data)

Upstream product

• 306972-97-4 (S)-2-Bromo-1-(3-bromo-4-methoxyphenyl)decan-1-one 

Downstream Products

• 2623-95-2 2-bromodecanoic acid 

Relevant articles and documents

Enantioselective synthesis of α-bromo acid derivatives and bromohydrins from tartrate derived bromoacetals

Bromination of the acetals 4 derived from aryl alkyl ketones, ArCOR, and (2R,3R)-tartaric acid results in bromoacetals 5 with 78-90% de. Hydrolysis of those compounds with Ar = 4-methoxyphenyl or 3-bromo-4-methoxyphenyl results, after recrystallisation, in α-bromoketones 8 with 66-98% ee which are shown to undergo the Baeyer-Villiger oxidation to α-bromoesters 9 with minimal racemisation, α-Bromoketone 8d is shown to undergo carbonyl reduction to threo-bromohydrin 15 with retention of stereochemistry.