2623-95-2

Basic information

• Product Name: 2-BROMODECANOIC ACID
• Synonyms: BROMODECANOIC ACID;2-BROMOCAPRIC ACID;2-BROMODECANOIC ACID;A-BROMODECANOIC ACID;A-BROMOCAPRIC ACID;ALPHA-BROMOCAPRIC ACID;2-bromo-decanoicaci
• CAS NO: 2623-95-2
• Molecular Formula: C₁₀H₁₉BrO₂
• Molecular Weight: 251.16
• EINECS: 220-086-5
• Mol File: 2623-95-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: 2°C
• Boiling Point: 116-118 °C0.05 mm Hg(lit.)
• Flash Point: 143.5 °C
• Appearance: /
• Density: 1.21 g/mL at 20 °C(lit.)
• Vapor Pressure: 0.000106mmHg at 25°C
• Refractive Index: n20/D 1.471
• PKA: 2.98±0.21(Predicted)
• BRN: 1767667
• CAS DataBase Reference: 2-BROMODECANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMODECANOIC ACID(2623-95-2)
• EPA Substance Registry System: 2-BROMODECANOIC ACID(2623-95-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 8-10
• HazardClass: IRRITANT
• Hazardous Substances Data: 2623-95-2(Hazardous Substances Data)

Usage

Definition

ChEBI: A bromo fatty acid that is decanoic acid carrying a single bromo substituent at position 2.

InChI:InChI=1/C10H19BrO2/c1-2-3-4-5-6-7-8-9(11)10(12)13/h9H,2-8H2,1H3,(H,12,13)

Upstream product

• 334-48-5 1-decanoic acid 
• 306973-02-4 3-Bromo-4-methoxyphenyl (S)-2-bromodecanoate 
• 306972-97-4 (S)-2-Bromo-1-(3-bromo-4-methoxyphenyl)decan-1-one 
• 112-13-0 n-decanoyl chloride 
• 99217-33-1 α-bromodecanoyl chloride 

Downstream Products

• 146793-36-4 2-mercapto-decanoic acid 
• 17702-88-4 rac-2-aminodecanoic acid 
• 7357-56-4 methyl ester of α-bromodecanoic acid 
• 101271-84-5 2-phenoxy-decanoic acid 
• 101867-23-6 2-Benzamino-decansaeure-⁽¹⁾ 
• 334-49-6 trans-2-decenoic acid 
• 67552-88-9 2-(2-Hydroxyethylamino)decanoic acid 
• 244093-65-0 1,5-di[2-(2'-carboxydecyloxy)phenoxy]-3-oxapentane 
• 244093-64-9 1,2-di[2-(2'-carboxydecyloxy)phenoxy]propane 
• 220150-47-0 1,2-di[2-(2'-carboxydecyloxy)phenoxy]ethane 

Relevant articles and documents

A NEW ALKAMIDE FROM PIPER SYLVATICUM

Sylvamide, a new amide derivative, has been isolated from the petrol extract of the seeds of Piper sylvaticum (Roxb.).From spectral and chemical studies its structure has been elucidated as N-isobutyl-4,5-dihydroxy-2(E)-decenamide. - Key Word Index: Piper sylvaticum; Piperaceae; seeds; sylvamide; N-isobutyl-4,5-dihydroxy-2(E)-decenamide.

1, 1, 1-tri (hydroxymethyl) ethane as coupling includes sub-surfactant and method of preparing the same

The invenetion relates to a preparation method of a ternary surface active agent adopting 1,1,1-tri(hydroxymethyl) ethane as a link group. A structural formula of the ternary surface active agent is as follows (described in specifications). The synthesis method includes a synthesis step of alpha-bromo-carboxylic acid, an esterification reaction step of the link group 1,1,1-tri(hydroxymethyl) ethane and an esterolysis reaction step. The synthesis process condition of the ternary surface active agent is as follows: 30% NaOH and tetrahydrofuran are used as a solvent to be subjected to reflux reaction for 5 to 7 hours.

Synthesis and characterization of novel phosphonocarboxylate inhibitors of RGGT

Phosphonocarboxylate (PC) analogs of the anti-osteoporotic drugs, bisphosphonates, represent the first class of selective inhibitors of Rab geranylgeranyl transferase (RabGGTase, RGGT), an enzyme implicated in several diseases including ovarian, breast and skin cancer. Here we present the synthesis and biological characterization of an extended set of this class of compounds, including lipophilic derivatives of the known RGGT inhibitors. From this new panel of PCs, we have identified an inhibitor of RGGT that is of similar potency as the most active published phosphonocarboxylate, but of higher selectivity towards prenyl pyrophosphate synthases. New insights into structural requirements are also presented, showing that only PC analogs of the most potent 3rd generation bisphosphonates inhibit RGGT. In addition, the first phosphonocarboxylate-derived GGPPS weak inhibitor is reported.