334-49-6 Usage
Description
TRANS-2-DECENOIC ACID, also known as (E)-2-Decenoic acid, is an unsaturated fatty acid with its double bond in the trans configuration. It is an intermediate metabolite in the fatty acid synthesis process and is found in royal jelly produced by honeybees. This clear, colorless to pale yellow liquid has a peach-orange, slightly waxy aroma and is known for its weak estrogenic activity, inhibiting the binding of 17β-estradiol to estrogen receptor β. It is also reported to be found in lamb, pork fat, black tea, and wort.
Uses
Used in Pharmaceutical Applications:
TRANS-2-DECENOIC ACID is used as a pharmaceutical agent for its weak estrogenic activity, which helps in inhibiting the binding of 17β-estradiol to estrogen receptor β. This property makes it a potential candidate for the development of treatments related to estrogen receptor β.
Used in Perfumery:
TRANS-2-DECENOIC ACID is used as a fragrance ingredient in the perfumery industry due to its peach-orange, slightly waxy aroma. Its unique scent adds a distinct and pleasant note to various perfume compositions.
Used in the Food Industry:
TRANS-2-DECENOIC ACID can be used in the food industry as a natural flavoring agent, taking advantage of its pleasant aroma to enhance the taste and smell of various food products.
Used in Cosmetics:
Due to its weak estrogenic activity, TRANS-2-DECENOIC ACID may also find applications in the cosmetics industry, potentially being used in the development of skincare products that target estrogen-related skin issues.
Check Digit Verification of cas no
The CAS Registry Mumber 334-49-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,3 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 334-49:
(5*3)+(4*3)+(3*4)+(2*4)+(1*9)=56
56 % 10 = 6
So 334-49-6 is a valid CAS Registry Number.
InChI:InChI=1S/C10H18O2/c1-2-3-4-5-6-7-8-9-10(11)12/h8-9H,2-7H2,1H3,(H,11,12)/b9-8+
334-49-6Relevant articles and documents
Synthesis of (±)tetrahydromyricoidine
Song, Jiangao,Hesse, Manfred
, p. 6797 - 6804 (1993)
A total synthesis of the spermidine alkaloid (±)-tetrahydromyricoidine (6) was achieved by using two ring enlargement reactions. The difficulties experienced in the second ring enlargement step, a transamidation reaction with a medium ring sized lactam bearing two bulky groups are discussed. These were overcome by altering the reaction sequence and the transamidation reaction was successfully carried out by at first deprotection of the Boc function. spermidine alkaloids; (±)-tetrahydromyricoidine; ring enlargement.
ANTI-BACTERIAL CALCIUM-DEPENDENT ANTIBIOTIC (CDA) ANALOGS AND METHODS OF TREATING BACTERIAL INFECTIONS
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Paragraph 0134; 0136, (2021/10/22)
Provided herein are calcium-dependent antibiotics (CDAs), as a novel therapeutic target for treating bacterial infections. The present invention also relates to pharmaceutical compositions comprising such compounds, and to methods of use thereof for combating bacteria and treating bacterial infections.
Convergent Synthesis of Calcium-Dependent Antibiotic CDA3a and Analogues with Improved Antibacterial Activity via Late-Stage Serine Ligation
Blasco, Pilar,Chen, Delin,Chen, Sheng,Li, Xuechen,Po, Kathy Hiu Laam
supporting information, (2020/06/29)
A convergent synthesis via the late-stage serine ligation of naturally occurring calcium-dependent antibiotic CDA3a and its analogues has been developed, which allowed us to readily synthesize the analogues with the variation on the lipid tail. Some analogues were found to show 100-500-fold higher antimicrobial activity than the natural compound CDA3a against drug resistant bacteria. This study will enhance our understanding of CDA3a and provide valuable antibacterial lead candidates for further development.
