307951-35-5

Basic information

• Product Name: 5-bromopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine-3-carboxylic acid methyl ester
• Synonyms: 5-bromopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine-3-carboxylic acid methyl ester
• CAS NO: 307951-35-5
• Molecular Weight: 306.118
• Mol File: 307951-35-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-bromopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine-3-carboxylic acid methyl ester(307951-35-5)
• EPA Substance Registry System: 5-bromopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine-3-carboxylic acid methyl ester(307951-35-5)

Safety Data

• Hazardous Substances Data: 307951-35-5(Hazardous Substances Data)

Upstream product

• 23612-48-8 2-methyl-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 1396319-74-6 (5E)-3-benzyl-5-[benzylamino-(1H-pyrrolo[2,3-b]pyridin-2-yl)-methylene]-3,5-dihydroimidazol-4-one 
• 1396319-75-7 (5E)-3-cyclohexyl-5-[cyclohexylamino-(1H-pyrrolo[2,3-b]pyridin-2-yl)-methylene]-3,5-dihydroimidazol-4-one 

Relevant articles and documents

Reaction of 2-bromomethylazoles and TosMIC: A domino process to azolopyrimidines. Synthesis of core tricycle of the variolins alkaloids

(matrix presented) A new reaction of N-protected 2-bromomethylazoles and tosylmethyl isocyanide (TosMIC) leading to the preparation of azolopyrimidines is described. This domino sequence was used to synthesize the pyrido[3′,2′:4,5]pyrrolo[1,2-c]pyrimidine core of alkaloids variolins from 4-methoxy-2-methylpyrrolo[2,3-b]pyrimidine in two steps.