308248-82-0

Basic information

• Product Name: 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione
• Synonyms: 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione
• CAS NO: 308248-82-0
• Molecular Weight: 292.765
• Mol File: 308248-82-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione(308248-82-0)
• EPA Substance Registry System: 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione(308248-82-0)

Safety Data

• Hazardous Substances Data: 308248-82-0(Hazardous Substances Data)

Upstream product

• 126-81-8 dimedone 
• 75039-59-7 2-dimethylaminomethylene-5,5-dimethylcyclohexane-1,3-dione 
• 1073-69-4 N-4-chlorophenylhydrazine 
• 1073-70-7 4-chlorophenylhydrazine hydrochloride 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 308248-91-1 1-(4-chlorophenyl)-6,6-dimethyl-4,5-dioxo-4,5,6,7-tetrahydroindazole 
• 37858-92-7 1-(4-chlorophenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H- indazol-4-one 

Relevant articles and documents

Carbodiimide mediated synthesis of new thiazolidin-4-ones and thiazinan-4-ones from thiosemicarbazone derivatives of 6,7-dihydro-1H-indazole- 4(5H )-ones

5,5-Dimethyl-2-[(2-substitutedphenylhydrazinyl)methylene]cyclohexane-1, 3-dione, obtained from heating dimedone with N,N'-dimethylformamide dimethyl acetal (DMF-DMA) and phenyl hydrazines, on cyclisation in ethanol gave 6,7-dihydro- 1H-indazol-4(5H )-ones

Synthesis and reactions of 1-(4-chloro-, 3-chloro-, 2-chloro-, 2,4-dichloro-, and 2,4-difluorophenyl)-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydroindazoles

Reaction of the potassium salt of 2-formyldimedone with hydrochlorides of 4-chloro-, 3-chloro-, 2-chloro-, 2,4-dichloro-, and 2,4-difluorophenylhydrazines gave the corresponding 2-arylhydrazinomethylene-dimedones which cyclized in acid media to 1-substituted 6,6-dimethyl-4-oxo-4,5,6,7-tetrahydroindazoles. Oxidation of the latter with selenious acid gave the corresponding 4,5-dioxo-4,5,6,7-tetrahydroindazoles which were further converted into 3-aryl-5,5-dimethyl-4,5-dihydro-3H-pyrazolo[4,3-a]phenazines and 2,6-diaryl-4,4-dimethyl-4,5-dihydro-1H(3H)-indazolo[4,5-g]imidazoles.