37858-92-7

Basic information

• Product Name: 1-(4-chlorophenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H- indazol-4-one
• Synonyms: 1-(4-chlorophenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H- indazol-4-one
• CAS NO: 37858-92-7
• Molecular Weight: 274.75
• Mol File: 37858-92-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(4-chlorophenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H- indazol-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H- indazol-4-one(37858-92-7)
• EPA Substance Registry System: 1-(4-chlorophenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H- indazol-4-one(37858-92-7)

Safety Data

• Hazardous Substances Data: 37858-92-7(Hazardous Substances Data)

Upstream product

• 126-81-8 dimedone 
• 1073-70-7 4-chlorophenylhydrazine hydrochloride 
• 308248-82-0 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione 

Downstream Products

• 308248-91-1 1-(4-chlorophenyl)-6,6-dimethyl-4,5-dioxo-4,5,6,7-tetrahydroindazole 

Relevant articles and documents

Ultrasound assisted regioselective synthesis, photophysical and structural studies of 1-substituted indazol-4(5H)-ones and enaminodiketones of dimedone

Enaminodiketone, obtained from reaction of dimedone with DMF-DMA, on reaction with nucleophiles such as amines, guanidine hydrochloride and substituted aromatic hydrazines furnished enaminodiketones, quinazolines and indazole derivatives respectively. The

Synthesis and reactions of 1-(4-chloro-, 3-chloro-, 2-chloro-, 2,4-dichloro-, and 2,4-difluorophenyl)-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydroindazoles

Reaction of the potassium salt of 2-formyldimedone with hydrochlorides of 4-chloro-, 3-chloro-, 2-chloro-, 2,4-dichloro-, and 2,4-difluorophenylhydrazines gave the corresponding 2-arylhydrazinomethylene-dimedones which cyclized in acid media to 1-substituted 6,6-dimethyl-4-oxo-4,5,6,7-tetrahydroindazoles. Oxidation of the latter with selenious acid gave the corresponding 4,5-dioxo-4,5,6,7-tetrahydroindazoles which were further converted into 3-aryl-5,5-dimethyl-4,5-dihydro-3H-pyrazolo[4,3-a]phenazines and 2,6-diaryl-4,4-dimethyl-4,5-dihydro-1H(3H)-indazolo[4,5-g]imidazoles.