30923-59-2

Basic information

• Product Name: Benzenemethanol, 2-hydroxy-, a-benzoate
• CAS NO: 30923-59-2
• Molecular Formula: C14H12O3
• Molecular Weight: 228.247
• Mol File: 30923-59-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2-hydroxy-, a-benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-hydroxy-, a-benzoate(30923-59-2)
• EPA Substance Registry System: Benzenemethanol, 2-hydroxy-, a-benzoate(30923-59-2)

Safety Data

• Hazardous Substances Data: 30923-59-2(Hazardous Substances Data)

Upstream product

• 3277-27-8 diethyl benzoylphosphonate 
• 90-01-7 salicylic alcohol 
• 455-32-3 benzoyl fluoride 
• 18544-92-8 1-Trimethylsilanyloxy-2-trimethylsilanyloxymethyl-benzene 
• 98-88-4 benzoyl chloride 
• 2902-69-4 2,2,2-trichloroacetophenone 
• 3381-87-1 2-benzyloxybenzyl alcohol 
• 854169-15-6 1-benzoyloxymethyl-2-benzyloxy-benzene 
• 19820-51-0 2-benzoyloxy-benzaldehyde 

Downstream Products

• 64421-25-6 2-methoxybenzyl benzoate  

Relevant articles and documents

Organocatalytic selective benzoylation of alcohols with trichloromethyl phenyl ketone: Inverse selectivity in benzoylation of alcohols containing phenol or aromatic amine functionality

Trichloromethyl phenyl ketone benzoylates primary and secondary aliphatic alcoholic groups in compounds also containing a phenolic group in the presence of 2-10 mol % of PMDETA organocatalyst at room temperature in high yields and excellent selectivity. It also shows the potential to selectively benzoylate primary alcoholic groups of aminoarylalkanols and primary-secondary diols as well as primary amino group of alkyl amines in the presence of aryl amines under similar conditions. A rationale for the selectivity and efficiency of the reaction has been provided.

Efficient access to orthoquinols and their [4 + 2] cyclodimers via SIBX-mediated hydroxylative phenol dearomatization

(Chemical Equation Presented) SIBX, the nonexplosive formulation of the λ5-iodane 2-iodoxybenzioc acid (IBX), safely and efficiently mediates the hydroxylative dearomatization of various 2-alkylphenols and napthols into orthoquinols or their [4 + 2] cyclodimers. Reactions are typically run at room temperature using SIBX as a suspension in THF. Using these conditions, natural products such as the cyclodimer of the terpene carvacrol and, for the first time, the shikimate-derived (±)-grandifloracin were prepared in one step from their respective phenolic precursor.

DIALKYL ACYLPHOSPHONATES: A NEW ACYLATING AGENT OF ALCOHOLS

Diethyl benzoylphosphonate (1) underwent facile benzoylation of alcohols in the presence of DBU.Reactions of diols containing primary and secondary hydroxyl groups with 1 gave predominantly monobenzoates in which primary hydroxyl groups were highly selectively benzoylated.Related acylations were also described.