313-12-2 Usage
Description
2-AMINO-3-(TRIFLUOROMETHYL)BENZOIC ACID is an organic compound characterized by its unique molecular structure, featuring a benzoic acid backbone with an amino group at the 2nd position and a trifluoromethyl group at the 3rd position. 2-AMINO-3-(TRIFLUOROMETHYL)BENZOIC ACID is known for its potential applications in various chemical and pharmaceutical industries due to its distinct properties.
Uses
Used in Pharmaceutical Industry:
2-AMINO-3-(TRIFLUOROMETHYL)BENZOIC ACID is used as an intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of new drugs with specific therapeutic properties.
Used in Chemical Synthesis:
In the chemical industry, 2-AMINO-3-(TRIFLUOROMETHYL)BENZOIC ACID serves as a valuable intermediate for the syntheses of antimicrobial agents, such as benzoisothiazolones and dithiobis(benzamides). These compounds exhibit potent antimicrobial activities, making them useful in the development of new antibiotics and antifungal agents to combat drug-resistant infections.
Used in Research and Development:
Due to its unique chemical properties, 2-AMINO-3-(TRIFLUOROMETHYL)BENZOIC ACID is also utilized in research and development for the exploration of new chemical reactions and the synthesis of novel compounds with potential applications in various fields, including materials science, agrochemistry, and environmental science.
Check Digit Verification of cas no
The CAS Registry Mumber 313-12-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,1 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 313-12:
(5*3)+(4*1)+(3*3)+(2*1)+(1*2)=32
32 % 10 = 2
So 313-12-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H5BClFO2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,10-11H
313-12-2Relevant articles and documents
Benzenesulfonamide IDH mutant inhibitor, preparation method and application thereof
-
, (2020/09/23)
The invention discloses a benzenesulfonamide compound represented by a general formula (I) or a pharmaceutically acceptable salt thereof, a preparation method and application thereof. Compared with the prior art, the benzenesulfonamide compound disclosed by the invention can be used as an isocitrate dehydrogenase 2 (IDH2) mutant inhibitor. According to the invention, pharmacological experiment results show that the compound disclosed by the invention has an obvious inhibiting effect on the activity of an IDH2 mutant (mIDH2), can effectively inhibit the process of catalyzing alpha-ketoglutaricacid to generate 2-hydroxyglutaric acid by mIDH2, and can be used for preventing and/or treating various related diseases including cancers and the like caused by IDH2 mutation.
Antimicrobial activity of fluorinated 1,2-benzisothiazol-3(2H)-ones and 2,2'-dithiobis(benzamides)
Carmellino,Pagani,Pregnolato,Terreni,Pastoni
, p. 743 - 751 (2007/10/02)
Fluoro and trifluoromethyl derivatives of 1,2-benzisothiazol-3(2H)-ones and the 2,2'-dithiobis(benzamides) have been prepared and their antifungal and antibacterial activity evaluated. Several compounds were found highly active against fungi and Gram-positive microorganisms and a few derivatives displayed some activity against Gram-negative strains. Structure-activity relationships are proposed.
Oxidation von Isatinen zu Anthranilsaeureestern
Reissenweber, Gernot,Mangold, Dietrich
, p. 914 - 915 (2007/10/02)
-