313727-12-7

Basic information

• Product Name: 1-acetyl-7-[4-(N-morpholino)phenyl]-2,3-dihydro-1H-1-benzazepine-4-carboxylic acid
• Synonyms: 1-acetyl-7-[4-(N-morpholino)phenyl]-2,3-dihydro-1H-1-benzazepine-4-carboxylic acid
• CAS NO: 313727-12-7
• Molecular Weight: 392.455
• Mol File: 313727-12-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-acetyl-7-[4-(N-morpholino)phenyl]-2,3-dihydro-1H-1-benzazepine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-acetyl-7-[4-(N-morpholino)phenyl]-2,3-dihydro-1H-1-benzazepine-4-carboxylic acid(313727-12-7)
• EPA Substance Registry System: 1-acetyl-7-[4-(N-morpholino)phenyl]-2,3-dihydro-1H-1-benzazepine-4-carboxylic acid(313727-12-7)

Safety Data

• Hazardous Substances Data: 313727-12-7(Hazardous Substances Data)

Upstream product

• 313724-66-2 methyl 1-(tert-butoxycarbonyl)-7-[4-(N-morpholino)phenyl]-2,3-dihydro-1H-1-benzazepine-4-carboxylate 
• 313724-71-9 methyl 7-[4-(N-morpholino)phenyl]-2,3-dihydro-1H-1-benzazepine-4-carboxylate 
• 313724-31-1 methyl 7-bromo-1-(t-butoxycarbonyl)-1,2,3,4-tetrahydro-1-benzazepin-5-one-4-carboxylate 
• 313724-26-4 7-bromo-1-(t-butoxycarbonyl)-1,2,3,4-tetrahydro-1-benzazepin-5-one 
• 3951-89-1 7-bromo-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one 
• 52727-57-8 5-bromo-2-aminobenzoic acid methyl ester 
• 223526-84-9 methyl 5-bromo-2-{[(4-methylphenyl)sulfonyl]amino}benzoate 
• 90312-02-0 N-(2-hydroxymethylphenyl)-4-methylbenzenesulfonamide 
• 34159-05-2 N-(4-bromo-2-formylphenyl)-4-methylbenzenesulfonamide 
• 6590-65-4 N-(2-Formyl-phenyl)-4-methyl-benzenesulfonamide 
• 313739-35-4 methyl 7-bromo-5-hydroxy-1-[(4-methylphenyl)sulfonyl]-2,3-dihydro-1H-1-benzazepine-4-carboxylate 
• 943819-81-6 methyl 5-bromo-2-{(4-methoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino}benzoate 
• 313735-42-1 7-bromo-2,3-dihydro-1H-1-benzazepine-4-carboxylic acid 
• 313726-95-3 ethyl 7-bromo-1-[(4-methylphenyl)sulfonyl]-2,3-dihydro-1H-1-benzazepine-4-carboxylate 

Relevant articles and documents

Preparation of a 1-unsubstituted-2,3-dihydro-1-benzazepine derivative

We developed a three-step method of producing a 1-unsubstituted-2,3-dihydro-1-benzazepine derivative (2) from 11. The alkylation of 9, obtained from 11, and the subsequent intramolecular condensation of 12 in dialkyl carbonate with a metal alcoholate were

BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF

Compounds of the general formula (I): or salts thereof, which exhibit CCR5 antagonism and exert preventive and therapeutic effects against HIV infections: wherein R1 is a 5- to 6-membered aromatic ring which bears a substituent represented by the general formula: R-Z1-X-Z2- (wherein R1 is hydrogen or optionally substituted hydrocarbyl; X is optionally substituted alkylene; and Z1 and Z2 are each a heteroatom) and may be further substituted, with R being optionally bonded to the aromatic ring to form another ring; Y is optionally substituted imino; and R2 and R3 are each optionally substituted aliphatic hydrocarbyl or an optionally substituted hetero-alicyclic group.