314-41-0 Usage
Description
2,3,4,6-TETRAFLUORONITROBENZENE is a yellow liquid with molluscicidal activity against Biomphalaria glabrata and has been studied for its palladium-catalyzed cross-coupling reactions with alkyne derivatives. It also undergoes reactions with 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene in the presence of water molecules in acetonitrile.
Uses
Used in Chemical Synthesis:
2,3,4,6-TETRAFLUORONITROBENZENE is used as a chemical intermediate for the synthesis of various compounds due to its reactive nature and ability to undergo palladium-catalyzed cross-coupling reactions with alkyne derivatives.
Used in Pest Control:
2,3,4,6-TETRAFLUORONITROBENZENE is used as a molluscicide for the control of Biomphalaria glabrata, a snail species that serves as an intermediate host for the parasitic flatworm Schistosoma mansoni, which causes schistosomiasis in humans.
Used in Pharmaceutical Industry:
2,3,4,6-TETRAFLUORONITROBENZENE is used as a starting material for the development of new pharmaceutical compounds, given its unique chemical properties and potential for further reactions and modifications.
Check Digit Verification of cas no
The CAS Registry Mumber 314-41-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,1 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 314-41:
(5*3)+(4*1)+(3*4)+(2*4)+(1*1)=40
40 % 10 = 0
So 314-41-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H7FO2/c1-5-3-2-4-6(7(5)9)8(10)11/h2-4H,1H3,(H,10,11)
314-41-0Relevant articles and documents
-
Coe,P.L. et al.
, p. 2323 - 2324 (1966)
-
HETEROCYCLIC SULFONAMIDE DERIVATIVES
-
Page/Page column 26; 27, (2013/02/27)
The present invention relates to compounds (I) and pharmaceutically acceptable salts thereof. The compounds have been demonstrated as inhibitors of MEK and therefore may be useful in the treatment of hyperproliferative diseases like cancer and inflammation.
Nitration of Strongly Deactivated Aromatics with Superacidic Mixed Nitric-Triflatoboric Acid (HNO3/2CF3SO3H-B(O3SCF3)3)
Olah, George A.,Orlinkov, Alexander,Oxyzoglou, Alexandros B.,Prakash, G. k. Surya
, p. 7348 - 7350 (2007/10/03)
The nitration of various deactivated arenes (including methanesulfonyl-, nitro-, and polyhalobenzenes) was carried out in good yield with mixed nitric-triflatoboric superacid.For example pentafluorobenzene gave pentafluoronitrobenzene in 99percent yield, nitrobenzene to m-dinitrobenzene in 92percent selectivity with 85percent overall yield, and methyl phenyl sulfone gave only the m-nitro isomer in 78percent isolated yield.Thus the new nitrating system gives high regioselectivity and yields under generally mild reaction conditions.The reagent system is compatible with many functional groups of arenes.
