3155-01-9

Basic information

• Product Name: 3-hydroxy-3-phenyl-butan-2-one
• Synonyms: 3-hydroxy-3-phenyl-butan-2-one
• CAS NO: 3155-01-9
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• Mol File: 3155-01-9.mol
• Article Data: 30

Chemical Properties

• Boiling Point: 267.1°Cat760mmHg
• Flash Point: 111.2°C
• Appearance: /
• Density: 1.089g/cm³
• Vapor Pressure: 0.00414mmHg at 25°C
• Refractive Index: 1.525
• PKA: 12.40±0.29(Predicted)
• CAS DataBase Reference: 3-hydroxy-3-phenyl-butan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-3-phenyl-butan-2-one(3155-01-9)
• EPA Substance Registry System: 3-hydroxy-3-phenyl-butan-2-one(3155-01-9)

Safety Data

• Hazardous Substances Data: 3155-01-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12O2/c1-8(11)10(2,12)9-6-4-3-5-7-9/h3-7,12H,1-2H3

Upstream product

• 127-66-2 2-Phenyl-3-butyn-2-ol 
• 6051-52-1 2-phenylbut-3-en-2-ol 
• 2674-04-6 diphenyl cadmium 
• 431-03-8 dimethylglyoxal 
• 71-43-2 benzene 
• 6007-26-7 2-methyl-1,3-dithian 
• 98-86-2 acetophenone 
• 515-30-0 2-phenyllactic acid 
• 917-54-4 methyllithium 
• 56955-40-9 acetic acid 1-methyl-2-oxo-1-phenyl-propyl ester 
• 61031-55-8 3-cyclohexyl-4-hydroxy-5,5-dimethyl-4-phenyl-oxazolidin-2-one 
• 75-36-5 acetyl chloride 
• 82571-41-3 tert-butyl hydrazone of acetaldehyde 
• 61031-52-5 4-hydroxy-3,5,5-trimethyl-4-phenyl-oxazolidin-2-one 

Downstream Products

• 101255-75-8 2-hydroxy-2-phenyl-5-piperidino-pentan-3-one; hydrochloride 
• 100706-38-5 1-acetoxy-3-hydroxy-3-phenyl-butan-2-one semicarbazone 
• 100054-40-8 optically inactive 3-methylamino-2-phenyl-butan-2-ol 
• 64969-62-6 methyl-(1-methyl-2-phenyl-propyl)-amine 
• 13562-17-9 5-(1-Hydroxy-cyclopentyl)-3-methyl-2-phenyl-pentin-⁽⁴⁾-diol-(2,3) 
• 4564-83-4 Acetic acid (1S,2S)-2-hydroxy-1-methyl-2-phenyl-propyl ester 
• 13562-18-0 2,3-Dihydroxy-5-(1-hydroxy-cyclohexyl)-3-methyl-2-phenyl-pentin-⁽⁴⁾ 
• 7476-35-9 3-[(E)-Butylimino]-2-phenyl-butan-2-ol 
• 13799-51-4 3,6-Dimethyl-2-phenyl-2,3,6-trihydroxy-heptin-⁽⁴⁾ 
• 13562-16-8 3,6-Dimethyl-2,3,6-trihydroxy-2-phenyl-octin-⁽⁴⁾ 
• 72420-48-5 6-methyl-6-phenyltetrahydropyran-2,3,5-trione 
• 109916-58-7 2-Methyl-2-phenyl-furan-3-one 
• 7473-98-5 2-hydroxy-2-methylpropiophenone 
• 72429-82-4 methyl 4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylate 

Relevant articles and documents

Novel routes to N-amino-1H-pyrrolo[2,3-b]pyridines from α-hydroxyarylalkyl ketones and hydrazines

Treatment of 3-hydroxy-3-(3-pyridyl)butan-2-one hydrazone with polyphosphoric acid gave 1-amino-2,3-dimethyl-1H-pyrrolo[2,3-b]pyridine. An analogous reaction with 2,4-dinitrophenylhydrazone of the same ketone yielded 1-(2,4-dinitrophenyl)-3-methyl-4-(3-pyridyl)pyrazole.

An efficient and recyclable AgNO3/ionic liquid system catalyzed atmospheric CO2 utilization: Simultaneous synthesis of 2-oxazolidinones and α-hydroxyl ketones

Oxazolidinones and α-hydroxyl ketones are two series of fine chemicals that have been generally utilized in biological, pharmaceutical, and synthetic chemistry. Herein, a AgNO3/ionic liquid (IL) catalytic system was developed for the simultaneous synthesis of these compounds through the atom-economical three-component reactions of propargyl alcohols, 2-aminoethanols, and CO2. Notably, this system behaved excellent catalytic activity with the lowermost metal loading of 0.25 mol%. Meanwhile, it is the first reported metal-catalyzed system that could efficiently work under atmospheric CO2 pressure and be recycled at least five times. Evaluation of the green metrics proved the AgNO3/IL-catalyzed processes to be relatively more sustainable and greener than the other Ag-catalyzed examples. Further mechanistic investigations revealed the derivative active species of N-heterocyclic carbene (NHC) silver complexes and CO2 adducts generated during the process. Subsequently, their reactivity in this reaction was assessed for the first time, which was finally identified as beneficial for the catalytic activity.

A green and recyclable CuSO4·5H2O/ionic liquid catalytic system for the CO2-promoted hydration of propargyl alcohols: an efficient assembly of α-hydroxy ketones

α-Hydroxy ketones are important building blocks in biological, pharmaceutical and synthetic chemistry. In this work, diverse α-hydroxy ketones were efficiently constructed through the CO2-promoted hydration process of propargyl alcohols, which was catalyzed by a system consisted of economical CuSO4·5H2O and a green 1-butyl-3-methylimidazolium acetate ionic liquid. Particularly, this catalytic system exhibited excellent activity under atmospheric CO2 or even mimetic flue gas (20 vol% of CO2). Moreover, this system employed the lowest metal loading ever reported (0.004–0.25 mol%) meanwhile reached the highest turnover number (11700) for the target hydration reaction. Additionally, this is the first reported Cu catalytic system with reliable recyclability, which could be easily reused at least 6 times with yields higher than 85%.

ELECTRO-OPTIC POLYMER

The present invention provides an electro-optic polymer (EO polymer) comprising an electro-optic molecule (EO molecule) and a base polymer. The EO polymer of the present invention has good performance over the entire optical communication wavelength range