3158-74-5

Basic information

• Product Name: 2-CYCLOPROPYLBENZOIC ACID
• Synonyms: AKOS BAR-1431;2-CYCLOPROPYLBENZOIC ACID
• CAS NO: 3158-74-5
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.19
• Mol File: 3158-74-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 102-106 °C
• Boiling Point: 282℃
• Flash Point: 131℃
• Appearance: /
• Density: 1.248
• PKA: 4.11±0.36(Predicted)
• CAS DataBase Reference: 2-CYCLOPROPYLBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYCLOPROPYLBENZOIC ACID(3158-74-5)
• EPA Substance Registry System: 2-CYCLOPROPYLBENZOIC ACID(3158-74-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 3158-74-5(Hazardous Substances Data)

Usage

General Description

2-Cyclopropylbenzoic acid is a white crystalline solid with the chemical formula C10H10O2. It is a derivative of benzoic acid with a cyclopropyl group attached to the benzene ring. 2-CYCLOPROPYLBENZOIC ACID is used in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in the production of various organic compounds. 2-Cyclopropylbenzoic acid is known for its potential biological activity and is being researched for its potential pharmaceutical applications. It is important to handle and store this compound with care, as it may pose health and environmental hazards if not properly managed.

Upstream product

• 20034-51-9 2-cyclopropylbenzaldehyde 
• 3155-00-8 2-cyclopropylbenzamide 
• 124-38-9 carbon dioxide 
• 57807-28-0 1-bromo-2-cyclopropylbenzene 
• 2039-88-5 2-bromostyrene 
• 873-49-4 cyclopropylbenzene 
• 892390-51-1 C₁₅H₂₀NO⁽¹⁺⁾*I^(1-) 
• 6091-64-1 2-bromobenzoic acid ethyl ester 
• 148438-01-1 methyl 2-cyclopropylbenzoate 
• 610-94-6 2-bromobenzoic acid methyl ester 

Downstream Products

• 1689-09-4 3,3-Dimethyl-3H-isobenzofuran-1-one 
• 68944-81-0 4-methyl-1H-isochromen-1-one 
• 918867-74-0 2-cyclopropyl-N-tosylbenzamide 
• 918867-71-7 N-tert-butyl-2-cyclopropylbenzamide 
• 918867-78-4 N-(tert-butyl)-2-(prop-1-en-2-yl)benzamide 
• 918867-73-9 2-cyclopropyl-N-phenylbenzamide 
• 918867-69-3 N-butyl-2-cyclopropylbenzamide 
• 918867-72-8 N-benzyl-2-cyclopropylbenzamide 
• 918867-70-6 N-(4-chlorophenethyl)-2-cyclopropylbenzamide 
• 73109-01-0 3-methyl-2-phenylisoquinolin-1(2H)-one 
• 53890-83-8 2-phenyl-3,3-dimethylisoindoline-1-one 
• 39774-23-7 1-oxo-3-methyl-2-phenylmethyl-1,2-dihydroisoquinoline 
• 50564-92-6 2-benzyl-3,3-dimethylisoindolin-1-one 

Relevant articles and documents

MODIFIED PROTEINS AND PROTEIN DEGRADERS

Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.

NOVEL COMPOUNDS

A compound of Formula (I) and pharmaceutically and/or veterinarily acceptable derivatives thereof, wherein: R1 is H, C1-6alkyl, - C(A)D, C3-8cycloalkyl, aryl, het, aryl-C1-4alkyl or het-C1-4/sub

2-Cyclopropylbenzoic acids in the synthesis of phthalides and 3,4-dihydroisocoumarins

2-Cyclopropylbenzoic acids, under the action of strong protic acids (FSO3H, H2SO4), are convened to 3-ethylphthalidium ions. In solutions in these inorganic acids, the 3-ethylphthalidium ions are isomerized to 3-methyl-3,4