39774-23-7

Basic information

• Product Name: 1(2H)-Isoquinolinone, 3-methyl-2-(phenylmethyl)-
• CAS NO: 39774-23-7
• Molecular Formula: C17H15NO
• Molecular Weight: 249.312
• Mol File: 39774-23-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1(2H)-Isoquinolinone, 3-methyl-2-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Isoquinolinone, 3-methyl-2-(phenylmethyl)-(39774-23-7)
• EPA Substance Registry System: 1(2H)-Isoquinolinone, 3-methyl-2-(phenylmethyl)-(39774-23-7)

Safety Data

• Hazardous Substances Data: 39774-23-7(Hazardous Substances Data)

Upstream product

• 19164-60-4 7-methylbicyclo[4.2.0]octa-1,3,5-trien-7-ol 
• 3173-56-6 benzyl isothiocyanate 
• 100-46-9 benzylamine 
• 70913-21-2 (E)-1-bromo-2-(2-methylethenyl)benzene 
• 68692-74-0 (E)-2-(prop-1-en-1-yl)benzoic acid 
• 1351765-65-5 (E)-N-benzyl-2-(prop-1-enyl)benzamide 
• 16859-59-9 3-hydroxy-1(3H)-isobenzofuranone 
• 933-88-0 ortho-toluoyl chloride 
• 5955-73-7 2-methylbenzoyl cyanide 
• 3158-74-5 2-cyclopropylbenzoic acid 
• 57807-28-0 1-bromo-2-cyclopropylbenzene 
• 918867-72-8 N-benzyl-2-cyclopropylbenzamide 
• 73178-23-1 N-benzyl-2-iodobenzamide 
• 53915-69-8 allenyltributylstannane 

Relevant articles and documents

Light-driven selective aerobic oxidation of (iso)quinoliniums and related heterocycles

Selective C1-H/C4-H carbonylation of N-methylene iminium salts, catalyzed by visible-light photoredox and oxygen in the air, has been reported. A ruthenium complex acts as a chemical switch to conduct two different reaction pathways and to afford two diff

Regioselective Pd-catalyzed aerobic aza-Wacker cyclization for preparation of isoindolinones and isoquinolin-1(2 H)-ones

A switchable regioselective intramolecular aerobic aza-Wacker cyclization catalyzed by palladium is presented. Isoindolinones or isoquinolin-1(2H)-ones could be prepared selectively from the same substrates using different catalysts. The type and steric hindrance of the ligands may be the variables most significant for regiocontrol.

Regioselective synthesis of 1,4,6-trisubstituted-2-pyridinones and 2,3-disubstituted (2H)-isoquinolin-1-ones via tandem stille reaction/ heterocyclisation

A general route to 1,4,6-trisubstituted 2-pyridinones and 2,3-disubstituted (2H)-isoquinolin-1-ones from (Z)-3-iodovinylic amides 1a-h and 2-iodo N-substituted benzamides 2a-f is described, including compounds bearing a substituent on the aromatic ring. Treatment of (Z)-β-iodovinylic amides 1a-h and 2-iodobenzamides 2a-f with various allenyltributyltin reagents in the presence of palladium acetate, triphenylphosphine and tetrabutylammonium bromide in acetonitrile provided good yields of the corresponding 1,4,6-trisubstituted 2-pyridinones 3a-k and 2,3-disubstituted (2H)-isoquinolin-1-ones 4a-i via tandem Stille reaction and 6-endo-dig azacyclisation. Georg Thieme Verlag Stuttgart.