3166-00-5

Basic information

• Product Name: N-AMIDINOBENZAMIDE
• Synonyms: N-AMIDINOBENZAMIDE;Benzamide, N-(aminoiminomethyl)- (9CI);1-Benzoylguanidine;2-Benzoylguanidine;N-(Aminoiminomethyl)benzamide;N-(diaminomethylene)benzamide;N-(diaminomethylidene)benzamide;N-[bis(azanyl)methylidene]benzamide
• CAS NO: 3166-00-5
• Molecular Formula: C₈H₉N₃O
• Molecular Weight: 163.18
• Product Categories: AMIDE
• Mol File: 3166-00-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 342.4°Cat760mmHg
• Flash Point: 160.9°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 7.57E-05mmHg at 25°C
• Refractive Index: 1.611
• CAS DataBase Reference: N-AMIDINOBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-AMIDINOBENZAMIDE(3166-00-5)
• EPA Substance Registry System: N-AMIDINOBENZAMIDE(3166-00-5)

Safety Data

• Hazardous Substances Data: 3166-00-5(Hazardous Substances Data)

Usage

General Description

N-Amidinobenzamide is a chemical compound with the molecular formula C8H8N2O. It is a benzamide derivative with an amidine functionality. N-Amidinobenzamide is commonly used as a reagent in organic synthesis and as a building block in the preparation of various pharmaceutical compounds. It has been found to exhibit potential biological activities, including anticancer and antiviral properties. Additionally, N-Amidinobenzamide has been studied for its potential use as an inhibitor of a specific enzyme pathway involved in the development of certain diseases. Due to its versatile and pharmacologically relevant properties, N-Amidinobenzamide continues to be an area of research interest in the field of medicinal chemistry and drug development.

InChI:InChI=1/C8H9N3O/c9-8(10)11-7(12)6-4-2-1-3-5-6/h1-5H,(H4,9,10,11,12)

Upstream product

• 50-01-1 guanidine hydrochloride 
• 98-88-4 benzoyl chloride 
• 93-89-0 benzoic acid ethyl ester 
• 113-00-8 guanidine nitrate 
• 7788-14-9 5-phenyl-1,2,4-oxadiazol-3-amine 
• 74764-17-3 2-[(pyridin-2-yl)amino]ethylamine 
• 614-23-3 N-benzoylthiourea 

Downstream Products

• 13796-90-2 4-benzyl-6-phenyl-[1,3,5]triazin-2-ylamine 
• 537698-16-1 N¹-benzoyl-N³-phenylsulfonylguanidine 
• 101281-83-8 N-(N-acetyl-sulfanilyl)-N'-benzoyl-guanidine 
• 57053-67-5 N-benzoylcarbamimidoyl-thioacetamide 
• 27182-54-3 5-phenyl-1,2,4-thiadiazol-3-amine 
• 119294-51-8 4-Phenyl-6-pyridin-4-yl-[1,3,5]triazin-2-ylamine 
• 114811-82-4 4-[2-(4-Amino-6-phenyl-[1,3,5]triazin-2-yl)-ethyl]-2,6-di-tert-butyl-phenol 

Relevant articles and documents

Iodine-mediated multi-component reactions: Readily access to tetrazoles and guanidines

Environmentally benign syntheses of One-pot sequential reactions of benzoyl chloride with amines followed by the treatment of molecular I2 reagent under basic conditions provide benzoyl tetrazoles and guanidines in moderate to excellent yields. This one-pot synthesis has several advantages such as mild reaction conditions, short reaction time, convenient workup, high yields, using cheap and readily available reagent molecular Iodine. In addition, functional group tolerance has been explored.

IMIDAZOLYL ALKYL GUANIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS

New imidazolylalkyl-guanidine derivatives are described, which by virtue of their agonistic action on histamine-H 2 receptors and in part also due to their additional H 1-antagonistic receptor activity can be used in the treatment of cardiac diseases, certain forms of hypertension and diseases of arterial occlusion.These imidazolylalkyl-guanidine derivatives correspond to the general formula I: STR1