31696-84-1Relevant articles and documents
Base-free synthesis of 1,3,5-triazines via aerobic oxidation of alcohols and benzamidine over a recyclable OMS-2 catalyst
Shen, Jian,Meng, Xu
, p. 58 - 63 (2019/05/15)
By using 4Na2SO4·2H2O2·NaCl as a reductant, manganese oxide octahedral molecular sieve (OMS-2)with enhanced surface area and mixed valence was prepared successfully. OMS-2 showed excellent catalytic ability towards aerobic oxidative synthesis of 1,3,5-triazines from benzyl alcohols and benzamidine. Methyl benzenes, DMF and DMSO could also be employed as substrates to react with benzamidine offering triazines under the heterogeneous conditions. The catalytic system features base-free conditions, broad substrate scope, high chemoselectivity, operational simplicity, catalyst recyclability and utilization of O2 as the green oxidant.
An alternatively metal-free synthesis of 1,3,5-triazines or 1,2,4-thiadiazoles from benzyl chlorides and benzylamines mediated by elemental sulfur
Zhang, Yurong,Liu, Yafei,Zhang, Jun,Gu, Ren,Han, Shiqing
supporting information, (2019/11/11)
An elemental sulfur mediated reaction of benzyl chlorides with benzylamines is developed, which allows the practical synthesis of valuable 1,3,5-triazines. This protocol that is metal free, ligand free, and uses inexpensive elemental sulfur as oxidant or raw material displays mild reaction conditions, a broad substrate scope and moderate to good yields. Moreover, the modified sulfur-mediated reaction system can also be used to synthesize 1,2,4-thiadiazoles, by simply switching the stoichiometry of sulfur powder from 0.75 equivalents to 5 equivalents.
Direct oxidative coupling of amidine hydrochlorides and methylarenes: TBHP-mediated synthesis of substituted 1,3,5-triazines under metal-free conditions
Guo, Wei
supporting information, p. 10285 - 10289 (2015/10/28)
Various 2,4,6-trisubstituted 1,3,5-triazines were smoothly formed via TBHP-mediated direct oxidative coupling of amidine and methylarenes. This tandem oxidation-imination-cyclization transformation exhibits a straightforward protocol to prepare 1,3,5-triazines from easily available starting materials and green oxidants under metal-free conditions.