16216-13-0

Basic information

• Product Name: 2'-METHYL-2-PHENYLACETOPHENONE
• Synonyms: 2'-METHYL-2-PHENYLACETOPHENONE
• CAS NO: 16216-13-0
• Molecular Formula: C₁₅H₁₄O
• Molecular Weight: 210.27
• Mol File: 16216-13-0.mol
• Article Data: 40

Chemical Properties

• Boiling Point: 337.5°C at 760 mmHg
• Flash Point: 144.8°C
• Appearance: /
• Density: 1.062g/cm³
• Vapor Pressure: 0.000105mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: 2'-METHYL-2-PHENYLACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-METHYL-2-PHENYLACETOPHENONE(16216-13-0)
• EPA Substance Registry System: 2'-METHYL-2-PHENYLACETOPHENONE(16216-13-0)

Safety Data

• Hazardous Substances Data: 16216-13-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H14O/c1-12-7-5-6-10-14(12)15(16)11-13-8-3-2-4-9-13/h2-10H,11H2,1H3

Upstream product

• 118-90-1 ortho-methylbenzoic acid 
• 103-82-2 phenylacetic acid 
• 460-19-5 ethanedinitrile 
• 6921-34-2 benzylmagnesium chloride 
• 529-19-1 2-Methylbenzonitrile 
• 87-24-1 ethyl 2-methylbenzoate 
• 527-85-5 o-Methylbenzamid 
• 908094-04-2 phenyldiazomethane 
• 529-20-4 2-methylphenyl aldehyde 
• 1589-82-8 phenylmagnesium bromide 
• 22817-11-4 1-(2-methylphenyl)-2-phenylethanol 
• 131833-62-0 dibenzyl-d5 ketone 
• 102-04-5 1,3-Diphenylpropanone 
• 17310-32-6 (CH₃C₆H₄)2Cd 

Downstream Products

• 56705-38-5 2,3-diphenyl-2-butanol 
• 16216-14-1 o-methylbenzil 
• 90137-70-5 1-chloro-1,2-diphenyl-propene 
• 74942-20-4 2-bromo-2-phenyl-1-(o-tolyl)ethanone 
• 77989-08-3 3-phenyl-4-o-tolyl-1,2,5-thiadiazole 
• 31696-84-1 2,4-diphenyl-6-(o-tolyl)-1,3,5-triazine 
• 527-85-5 o-Methylbenzamid 
• 129448-69-7 1-(2-methylphenyl)-2-phenyl-3-(3-methoxyphenyl)-1-propanone 
• 16619-12-8 2-phenyl-indan-1-one 
• 74942-21-5 2-amino-5-phenyl-4-(o-tolyl)thiazole 
• 74942-22-6 5-phenyl4-(o-tolyl)thiazole 
• 1283118-43-3 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-6-o-tolyl-3,4-dihydropyrimidin-2(1H)-one 
• 36374-51-3 2-(Phenylacetyl)phenylessigsaeure 

Relevant articles and documents

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Palladium-catalyzed synthesis of α-aryl acetophenones from styryl ethers and aryl diazonium saltsviaregioselective Heck arylation at room temperature

Preparation of α-aryl acetophenones from styryl ethers and aryldiazonium salts is described. The reaction is catalyzed by palladium acetate at room temperature in the absence of ligand and base. The developed method is highly attractive in terms of reaction conditions, substrate scope, functional group tolerance and yields. Synthetic applications of the present method are demonstrated by preparing α-aryl indoles and 3-aryl isocoumarin from styryl ethers.

The organocatalytic enantiodivergent fluorination of β-ketodiaryl-phosphine oxides for the construction of carbon-fluorine quaternary stereocenters

Commercially available cinchona alkaloids that can catalyze the enantiodivergent fluorination of β-ketodiarylphosphine oxides were developed to construct carbon-fluorine quaternary stereocenters. This protocol features a wide scope of substrates and excellent enantioselectivities, and it is scalable.