31872-14-7

Basic information

• Product Name: 4-ethenyl-2,6-dimethoxyphenol
• Synonyms: 2,6-Dimethoxy-4-vinylphenol; 4-vinyl-2,6-dimethoxyphenol; phenol, 4-ethenyl-2,6-dimethoxy-
• CAS NO: 31872-14-7
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.2005
• Mol File: 31872-14-7.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 285.4°C at 760 mmHg
• Flash Point: 126.4°C
• Density: 1.113g/cm³
• Vapor Pressure: 0.00163mmHg at 25°C
• Refractive Index: 1.561
• CAS DataBase Reference: 4-ethenyl-2,6-dimethoxyphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethenyl-2,6-dimethoxyphenol(31872-14-7)
• EPA Substance Registry System: 4-ethenyl-2,6-dimethoxyphenol(31872-14-7)

Safety Data

• Hazardous Substances Data: 31872-14-7(Hazardous Substances Data)

Upstream product

• 141-82-2 malonic acid 
• 134-96-3 syringic aldehyde 
• 530-59-6 sinapinic acid 
• 1252786-17-6 C₄H₁₁N*C₁₁H₁₂O₅ 
• 1252786-19-8 C₂H₇NO*C₁₁H₁₂O₅ 
• 1252786-21-2 C₅H₁₁N*C₁₁H₁₂O₅ 
• 1252786-20-1 C₈H₁₁N*C₁₁H₁₂O₅ 
• 1252786-22-3 C₆H₁₃N*C₁₁H₁₂O₅ 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 33900-62-8 1-(4-Hydroxy-3,5-dimethoxyphenyl)ethanol 
• 65109-39-9 4-(2-(2,6-dimethoxyphenoxy)-1-hydroxyethyl)-2,6-dimethoxyphenol 
• 1530-32-1 ethyltriphenylphosphonium bromide 

Relevant articles and documents

Photoacid-Enabled Synthesis of Indanes via Formal [3 + 2] Cycloaddition of Benzyl Alcohols with Olefins

An environmentally friendly and highly diastereoselective method for synthesizing indanes has been developed via a metastable-state photoacid system containing catalytic protonated merocyanine (MEH). Under visible-light irradiation, MEH yields a metastable spiro structure and liberated protons, which facilitates the formation of carbocations from benzyl alcohols, thus delivering diverse molecules in the presence of various nucleophiles. Mainly, a variety of indanes could be easily obtained from benzyl alcohols and olefins, and water is the only byproduct.

New hybrids based on curcumin and resveratrol: Synthesis, cytotoxicity and antiproliferative activity against colorectal cancer cells

We synthesized twelve hybrids based on curcumin and resveratrol, and their structures were elucidated by spectroscopic analysis. The chemopreventive potential of these compounds was evaluated against SW480 human colon adenocarcinoma cells, its metastatic derivative SW620, along with the non-malignant CHO-K1 cell line. Among the tested compounds, hybrids 3e and 3i (for SW480) and 3a, 3e and 3k (for SW620) displayed the best cytotoxic activity with IC50 values ranging from 11.52 ± 2.78 to 29.33 ± 4.73 μM for both cell lines, with selectivity indices (SI) higher than 1, after 48 h of treatment. Selectivity indices were even higher than those reported for the reference drug, 5-fluorouracil (SI = 0.96), the starting compound resveratrol (SI = 0.45) and the equimolar mixture of curcumin plus resveratrol (SI = 0.77). The previous hybrids showed good antiproliferative activity.

METHOD OF SELECTIVELY OXIDIZING LIGNIN

A method of selectively reacting lignin or a lignin-derived reactant to yield an aromatic product. The method includes the step of reacting lignin or a lignin-derived reactant with a molybdenum-containing catalyst, in a solvent, and optionally in the presence of an oxidant, for a time and a temperature wherein at least a portion of the lignin or lignin-derived reactant is selectively converted into an aromatic product, preferably coniferaldehyde and/or sinapaldehyde.