320-58-1 Usage
Description
(R)-2-acetamido-2-(2-fluorophenyl)propanoic acid, commonly known as flurbiprofen, is a non-steroidal anti-inflammatory drug (NSAID) characterized by its ability to alleviate pain, inflammation, and fever. As a propionic acid derivative, it operates by inhibiting the production of chemicals within the body that are responsible for these symptoms.
Uses
Used in Pharmaceutical Industry:
Flurbiprofen is utilized as an analgesic, anti-inflammatory, and antipyretic agent for managing various conditions such as arthritis, menstrual cramps, and dental pain. Its effectiveness in reducing inflammation and pain makes it a valuable asset in this application. However, due to potential serious side effects like gastrointestinal bleeding, kidney issues, and an increased risk of heart attack and stroke with long-term or high-dose usage, it should be administered with caution and under medical supervision.
Check Digit Verification of cas no
The CAS Registry Mumber 320-58-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 0 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 320-58:
(5*3)+(4*2)+(3*0)+(2*5)+(1*8)=41
41 % 10 = 1
So 320-58-1 is a valid CAS Registry Number.
320-58-1Relevant articles and documents
Native Amine-Directed ortho -C-H Halogenation and Acetoxylation /Condensation of Benzylamines
Chand-Thakuri, Pratibha,Alahakoon, Indunil,Liu, Daniel,Kapoor, Mohit,Kennedy, John F.,Jenkins, Kenneth W.,Rabon, Allison M.,Young, Michael C.
, p. 341 - 354 (2021/10/07)
Free or unfunctionalized benzylamines are well known to participate in C-H activation in the presence of palladium salts. Despite the ease with which these complexes can be activated, subsequent functionalization of the dimeric cyclometalates can be chall
5-AMINO[1,4]THIAZINES AS BACE 1 INHIBITORS
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Page/Page column 35, (2014/01/07)
The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
