320-88-7 Usage
Description
2,5-Bis(trifluoromethyl)nitrobenzene is an organic compound characterized by its clear yellow liquid appearance. It is known for its chemical structure that includes two trifluoromethyl groups and a nitro group attached to a benzene ring.
Uses
Used in Pharmaceutical Industry:
2,5-Bis(trifluoromethyl)nitrobenzene is used as an intermediate chemical for the synthesis of various pharmaceutical compounds. Its unique structure and properties make it a valuable building block in the development of new drugs.
Used in Antifungal Applications:
2,5-Bis(trifluoromethyl)nitrobenzene is used as an active ingredient in antifungal agents. It is particularly effective against a wide range of fungal infections due to its ability to disrupt the cell membrane and inhibit essential fungal enzymes, thus preventing fungal growth and proliferation.
Used in Chemical Synthesis:
In the chemical industry, 2,5-Bis(trifluoromethyl)nitrobenzene serves as a versatile intermediate for the synthesis of various organic compounds, including agrochemicals, dyes, and other specialty chemicals. Its trifluoromethyl and nitro groups can be further modified or functionalized to create a diverse array of products with specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 320-88-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 320-88:
(5*3)+(4*2)+(3*0)+(2*8)+(1*8)=47
47 % 10 = 7
So 320-88-7 is a valid CAS Registry Number.
320-88-7Relevant articles and documents
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Ross et al.
, p. 4967 (1953)
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PROCESS FOR PRODUCING 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE
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Page 6, (2008/06/13)
A process to produce 2,5-bis(trifluoromethyl)nitrobenzene in a high yield from an industrially easily available material by using a substance with which the reaction operation is simple and handling is easy, with a small number of steps under moderate reaction conditions, is provided. 1,4-bis(trifluoromethyl)benzene is nitrated by means of nitric acid in a solvent comprising as an essential component an acid selected from sulfuric acid having a sulfuric acid concentration of from 91 to 100 mass% and fuming sulfuric acid having a sulfur trioxide concentration of higher than 0 mass% and at most 20 mass%.
Synthesis of trifluoromethyl aryl derivatives via difluorocarbene precursors and nitro-substituted aryl chlorides
Duan, Jian-Xing,Su, De-Bao,Wu, Jian-Ping,Chen, Qing-Yun
, p. 167 - 170 (2007/10/02)
Treatment of aryl chlorides containing electron-withdrawing proups with methyl fluorosulfonyl difluoroacetate or methyl halodifluoroacetate in the presence of potassium fluoride and copper iodide gave the corresponding trifluoromethyl derivatives in moderate to high yields.