328-92-7

Basic information

• Product Name: 2,5-BIS(TRIFLUOROMETHYL)IODOBENZENE
• Synonyms: 2,5-BIS(TRIFLUOROMETHYL)IODOBENZENE;1,4-Bis(trifluoromethyl)-2-iodobenzene;alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-2-iodo-p-xylene
• CAS NO: 328-92-7
• Molecular Formula: C₈H₃F₆I
• Molecular Weight: 340
• Mol File: 328-92-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 89-92 °C
• Appearance: /
• Density: 1.904±0.06 g/cm3(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 2,5-BIS(TRIFLUOROMETHYL)IODOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-BIS(TRIFLUOROMETHYL)IODOBENZENE(328-92-7)
• EPA Substance Registry System: 2,5-BIS(TRIFLUOROMETHYL)IODOBENZENE(328-92-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 328-92-7(Hazardous Substances Data)

Usage

General Description

2,5-Bis(trifluoromethyl)iodobenzene is a chemical compound with the molecular formula C8H3F6I. It is a solid, crystalline substance that is commonly used in organic synthesis and as a reagent in chemical reactions. 2,5-BIS(TRIFLUOROMETHYL)IODOBENZENE is known for its high reactivity and ability to participate in various substitution and coupling reactions. It is often used as a reagent for introducing the trifluoromethyl group into organic molecules. 2,5-Bis(trifluoromethyl)iodobenzene is also used in pharmaceutical and agrochemical research as a building block for creating new compounds with potential biological activities. Due to its trifluoromethyl and iodine functional groups, this compound is highly valuable in synthetic chemistry for creating complex molecules.

Upstream product

• 328-93-8 2,5-bis(trifluoromethyl)aniline 
• 433-19-2 1,4-bis(trifluoromethyl)benzene 
• 320-88-7 1,4-Bis(trifluoromethyl)-2-nitro-benzene 

Downstream Products

• 128971-06-2 3-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenylamine 
• 128971-07-3 4-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenylamine 
• 128971-05-1 2-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenylamine 
• 128810-17-3 1-(4-methoxyphenyl)-4-[2,5-bis(trifluoromethyl)phenyl]-1,3-butadiyne 
• 128971-04-0 2-[4-(4-Methylsulfanyl-phenyl)-buta-1,3-diynyl]-1,4-bis-trifluoromethyl-benzene 
• 128971-10-8 {4-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenyl}-methyl-amine 
• 128810-15-1 1-(3-methoxyphenyl)-4-[2,5-bis(trifluoromethyl)phenyl]-1,3-butadiyne 
• 128971-09-5 {3-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenyl}-methyl-amine 
• 128971-08-4 {2-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenyl}-methyl-amine 
• 128971-03-9 2-[4-(2-Methoxy-phenyl)-buta-1,3-diynyl]-1,4-bis-trifluoromethyl-benzene 
• 1796930-46-5 dutasteride 

Relevant articles and documents

Single C?F Bond Cleavage of Trifluoromethylarenes with an ortho-Silyl Group

The transformation of a single C?F bond of trifluoromethylarenes bearing a hydrosilyl group at the ortho position was achieved. The activation of the hydrosilyl group with a trityl cation in the presence of nucleophiles allowed for selective C?F bond func

A scaleable synthesis of dutasteride: A selective 5α-reductase inhibitor

An improved and scaleable process for Dutasteride (1), a synthetic 4-azasteroid derivative essentially used for the treatment of prostate diseases, is described