320581-09-7

Basic information

• Product Name: Carbamic acid, (2-amino-1,1-dimethylethyl)-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, (2-amino-1,1-dimethylethyl)-, 1,1-dimethylethyl ester (9CI);(2-Amino-tert-butyl)carbamic acid tert-butyl ester;tert-Butyl (1-amino-2-methylpropan-2-yl)carbamate;(2-Amino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester;Carbamicacid,N-(2-amino-1,1-dimethylethyl)-,1,1-dimethylethylester
• CAS NO: 320581-09-7
• Molecular Formula: C₉H₂₀N₂O₂
• Molecular Weight: 188.2673
• Product Categories: N-BOC
• Mol File: 320581-09-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 275℃
• Flash Point: 120℃
• Appearance: /
• Density: 0.974
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 12.74±0.46(Predicted)
• CAS DataBase Reference: Carbamic acid, (2-amino-1,1-dimethylethyl)-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (2-amino-1,1-dimethylethyl)-, 1,1-dimethylethyl ester (9CI)(320581-09-7)
• EPA Substance Registry System: Carbamic acid, (2-amino-1,1-dimethylethyl)-, 1,1-dimethylethyl ester (9CI)(320581-09-7)

Safety Data

• Hazardous Substances Data: 320581-09-7(Hazardous Substances Data)

Usage

General Description

Carbamic acid, (2-amino-1,1-dimethylethyl)-, 1,1-dimethylethyl ester (9CI) is a chemical compound that is also known as t-butylcarbamic acid or Boc-amine. It is a derivative of carbamic acid and is commonly used in organic synthesis as a protecting group for amines. Carbamic acid, (2-amino-1,1-dimethylethyl)-, 1,1-dimethylethyl ester (9CI) is of interest to researchers in the pharmaceutical industry as it can be used in the synthesis of various drugs and pharmaceuticals. It is also used as a reagent in the production of peptide-based molecules. However, it should be handled with care as it can be hazardous if not used properly.

Upstream product

• 169954-67-0 (2-benzyloxycarbonylamino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester 
• 1373437-43-4 C₁₇H₂₂N₂O₄ 
• 24424-99-5 di-tert-butyl dicarbonate 
• 102520-97-8 2-((tert-butyloxycarbonyl)amino)-2-methylpropan-1-ol 
• 73470-46-9 tert-butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate 
• 30992-29-1 Boc-Aib-OH 

Downstream Products

• 845744-10-7 methyl 2-[({2-[(tert-butoxy)carbonylamino]-2-methylpropyl}amino)methyl]-4-(2-chlorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate 
• 743447-69-0 tert-butyl N-{2-[4-chloro-5-cyano-6-(3,5-dimethoxyphenylamino)pyrimidin-2-ylamino]-1,1-dimethylethyl}carbamate 
• 1301178-03-9 C₃₀H₄₁BrN₄O₃ 
• 169954-67-0 (2-benzyloxycarbonylamino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Tricyclic compound, pharmaceutical composition and application thereof

The present invention provides a tricyclic compound, an isomer thereof, a pharmaceutically acceptable salt, a pharmaceutical composition and an application thereof. The tricyclic compound has a structure represented by formula I, has a significant effect of inhibiting RET kinase activity, can effectively inhibit cancer cell proliferation, can be used as an RET kinase inhibitor, can be used for preparing medicines for treating RET kinase-mediated diseases, has a good treatment effect on RET kinase-mediated cancers and other diseases, and has a wide application prospect.

HETEROCYCLIC COMPOUNDS AS ARGINASE INHIBITORS

The present invention relates to heterocyclic compounds as arginase inhibitors, in particular to a compound represented by Formula (I), or a pharmaceutically acceptable salt, stereoisomer or tautomer, or prodrug thereof and a pharmaceutical composition comprising said compound.

Influence of achiral units with gem-dimethyl substituents on the helical character of aliphatic oligourea foldamers

The structures of various urea oligomers incorporating one or two central achiral 1,2-diamino-1,1-dimethylethane (DADME) units have been investigated in solution and in the crystalline state. These diamine monomers are analogous to the achiral helicogenic