32153-16-5

Basic information

• Product Name: 2-(benzylamino)-2-phenylacetamide
• CAS NO: 32153-16-5
• Molecular Formula: C₁₅H₁₆N₂O
• Molecular Weight: 240.3003
• Mol File: 32153-16-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 415.8°C at 760 mmHg
• Flash Point: 205.3°C
• Density: 1.145g/cm³
• Vapor Pressure: 4E-07mmHg at 25°C
• Refractive Index: 1.603
• CAS DataBase Reference: 2-(benzylamino)-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzylamino)-2-phenylacetamide(32153-16-5)
• EPA Substance Registry System: 2-(benzylamino)-2-phenylacetamide(32153-16-5)

Safety Data

• Hazardous Substances Data: 32153-16-5(Hazardous Substances Data)

Usage

Type of compound

Amide derivative

Parent compounds

Benzylamine and phenylacetic acid

Common use

Pharmaceutical research (potential drug candidate)

Analgesic

Pain-relieving

Anti-inflammatory

Reduces inflammation

Potential applications

a. Treating chronic pain
b. Treating inflammation

Research focus

Mechanism of action and therapeutic uses

Field

Drug research and development

Upstream product

• 56249-50-4 (Benzyl-trimethylsilanyl-amino)-phenyl-acetonitrile 
• 32153-18-7 2-(benzylamino)-2-phenylacetonitrile 
• 100-52-7 benzaldehyde 
• 100-46-9 benzylamine 
• 780-25-6 N-benzylidene benzylamine 
• 67067-96-3 ethyl ester of N-benzyl-α-phenylglycine 

Downstream Products

• 5728-12-1 4-phenyl-[1,2,5]thiadiazol-3-ol 
• 1859-51-4 N-Benzyl-α-phenylglycine 
• 2835-06-5 phenylglycin 
• 78139-30-7 3-Methoxy-4-phenyl-[1,2,5]thiadiazole 
• 78139-29-4 2-methyl-4-phenyl-1,2,5-thiadiazol-3-one 

Relevant articles and documents

Mechanochemical Activation of Iron Cyano Complexes: A Prebiotic Impact Scenario for the Synthesis of α-Amino Acid Derivatives

Mechanochemical activation of iron cyano complexes by ball milling results in the formation of HCN, which can be trapped and incorporated into α-aminonitriles. This prebiotic impact scenario can be extended by mechanochemically transforming the resulting α-aminonitriles into α-amino amides using a chemical route related to early Earth conditions.

AZOLE DERIVATIVES WITH ANTIMUSCARINIC ACTIVITY

The present invention relates to compounds of formula (I) wherein R1, R2, x, X, Y and B are as defined in the description for the treatment of muscarinic acetylcholine receptor mediated diseases, in particular M3 muscarinic receptor mediated diseases.

Studies on Mesoionic Compounds. Part 10. Synthesis and Chemical Properties of Mesoionic 1,2,5-Thiadiazolium-3-olates

The preparation of a novel mesoionic heterocycle is described; derivatives of 4-aryl-5-alkyl-1,2,5-thiadiazolium-3-olates (6a-f) are obtained by treatment of α-N-substituted aminophenylacetamides with sulphur monochloride followed by base.