321840-35-1

Basic information

• Product Name: (R)-1-(4-fluorophenyl)-2-(methoxy)ethylamine
• Synonyms: (R)-1-(4-fluorophenyl)-2-(methoxy)ethylamine
• CAS NO: 321840-35-1
• Molecular Weight: 169.199
• Mol File: 321840-35-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-1-(4-fluorophenyl)-2-(methoxy)ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(4-fluorophenyl)-2-(methoxy)ethylamine(321840-35-1)
• EPA Substance Registry System: (R)-1-(4-fluorophenyl)-2-(methoxy)ethylamine(321840-35-1)

Safety Data

• Hazardous Substances Data: 321840-35-1(Hazardous Substances Data)

Upstream product

• 19883-57-9 (S)-2-amino-2-(4-fluorophenyl)acetic acid 
• 174770-74-2 (R)-2-amino-2-(4-fluorophenyl)ethanol 
• 74-88-4 methyl iodide 
• 93939-74-3 (R)-2-(4-fluorophenyl)glycine 

Downstream Products

• 177948-41-3 1-tert-Butyloxycarbonyl-4-[(R)-1-(4-fluorophenyl)-2-methoxyethyl]aminopiperidine 

Relevant articles and documents

PYRAZOLE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSYNE KINASES

Compounds of formula (I): and their use in the inhibition of Trk activity are described.

Azetidine, pyrrolidine and piperidine derivatives

A class of substituted azetidine, pyrrolidine and piperidine derivatives are selective agonists of 5-HT1 -like receptors, being potent agonists of the human 5-HT1Dα receptor subtype whilst possessing at least a 10-fold selective affinity for the 5-HT1Dα receptor subtype relative to the 5-HT1Dβ subtype; they are therefore useful in the treatment and/or prevention of clinical conditions, in particular migraine and associated disorders, for which a subtype-selective agonist of 5-HT1D receptors is indicated, whilst eliciting fewer side-effects, notably adverse cardiovascular events, than those associated with non-subtype-selective 5-HT1D receptor agonists.