325796-72-3

Basic information

• Product Name: 1-(1-Benzyl-1H-indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol
• Synonyms: 1-(1-Benzyl-1H-indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol
• CAS NO: 325796-72-3
• Molecular Weight: 344.413
• Mol File: 325796-72-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(1-Benzyl-1H-indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-Benzyl-1H-indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol(325796-72-3)
• EPA Substance Registry System: 1-(1-Benzyl-1H-indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol(325796-72-3)

Safety Data

• Hazardous Substances Data: 325796-72-3(Hazardous Substances Data)

Upstream product

• 105170-27-2 2-bromo-5-methoxypyridine 
• 10511-51-0 1-Benzylindole-3-carboxaldehyde 
• 76066-07-4 2-bromo-3-methoxy-6-nitropyridine 
• 10167-97-2 2-amino-5-methoxypyridine 
• 100-39-0 benzyl bromide 
• 24100-18-3 2-bromo-3-methoxypyridine 
• 487-89-8 Indole-3-carboxaldehyde 

Downstream Products

• 325796-79-0 1-Benzyl-3-(5-methoxypyridin-2-ylmethyl)-2,3-dihydro-1H-indol 
• 325796-76-7 1-Benzyl-3-(5-methoxypyridin-2-ylmethyl)-1H-indol 
• 22187-96-8 5-methoxy-2-pyridinecarboxaldehyde 

Relevant articles and documents

Intramolecular alkylation of aromatic compounds, XXXIV: Synthesis of pyridinylmethyl indolines as potential precursors of ergolines

The carbinoles 3 prepared from the N-protected indolaldehydes 2 and bromomethoxypyridine 1 can smoothly be hydrogenolized to the lutidinylindoles 4 which in turn give the corresponding indolines 5 by NaCNBH3-reduction. Treatment of 3a by acid the trihetarylmethane 9 and 5-methoxypyridine-2-carboxaldehyde 10 are generated. The acetylpyridine 7 is found as a by-product of 3c. As by-product of the reduction the borane adduct 8 is detected.