3301-49-3 Usage
Description
5,4''-DIHYDROXY-3,7-DIMETHOXYFLAVONE, also known as 5-Hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one, is a naturally occurring flavonoid compound derived from the plant Psiadia trinervia. It is characterized by its unique chemical structure, which includes hydroxyl and methoxy groups, and is known for its antimicrobial properties.
Uses
Used in Pharmaceutical Industry:
5,4''-DIHYDROXY-3,7-DIMETHOXYFLAVONE is used as an antimicrobial agent for its ability to inhibit the growth of various microorganisms, including bacteria and fungi. This property makes it a potential candidate for the development of new drugs and therapies to combat infections and diseases caused by these pathogens.
Used in Natural Products Industry:
In the natural products industry, 5,4''-DIHYDROXY-3,7-DIMETHOXYFLAVONE is used as an active ingredient in the formulation of natural antimicrobial products, such as herbal remedies, supplements, and personal care items. Its natural origin and antimicrobial properties make it an attractive option for consumers seeking alternative, non-synthetic solutions for maintaining health and hygiene.
Used in Agricultural Industry:
5,4''-DIHYDROXY-3,7-DIMETHOXYFLAVONE can also be utilized in the agricultural industry as a natural antimicrobial agent to protect crops from bacterial and fungal infections. By incorporating this compound into agricultural practices, it may be possible to reduce the reliance on synthetic pesticides and promote more sustainable and environmentally friendly farming methods.
Check Digit Verification of cas no
The CAS Registry Mumber 3301-49-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,0 and 1 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3301-49:
(6*3)+(5*3)+(4*0)+(3*1)+(2*4)+(1*9)=53
53 % 10 = 3
So 3301-49-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H14O6/c1-21-11-7-12(19)14-13(8-11)23-16(17(22-2)15(14)20)9-3-5-10(18)6-4-9/h3-8,18-19H,1-2H3
3301-49-3Relevant articles and documents
Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates
Mei, Qinggang,Wang, Chun,Yuan, Weicheng,Zhang, Guolin
supporting information, p. 288 - 293 (2015/03/31)
A strategy for selective mono-, di- and tri-O-methylation of kaempferol, predominantly on the basis of selective benzylation and controllable deacetylation of kaempferol acetates, was developed. From the selective deacetylation and benzylation of kaempferol tetraacetate (1), 3,4′,5,-tri-O-acetylkaempferol (2) and 7-O-benzyl-3,4′5,-tri-O-acetylkaempferol (8) were obtained, respectively. By controllable deacetylation and followed selective or direct methylation of these two intermediates, eight O-methylated kaempferols were prepared with 51-77% total yields from kaempferol.
4'-Hydroxy-3-methoxyflavones with potent antipicornavirus activity
De Meyer,Haemers,Mishra,Pandey,Pieters,Vanden Berghe,Vlietinck
, p. 736 - 746 (2007/10/02)
4'-Hydroxy-3-methoxyflavones are natural compounds with known antiviral activities against picornaviruses such as poliomyelitis and rhinoviruses. In order to establish a structure-activity relationship a series of analogues were synthesized, and their antiviral activities and cytotoxicities were compared with those of flavones from natural origin. The 4'-hydroxyl and 3-methoxyl groups, a substitution in the 5 position and a polysubstituted A ring appeared to be essential requirements for a high activity. The most interesting compound was 4',7-dihydroxy-3-methoxy-5,6-dimethylflavone possessing in vitro TI99 values of > 1000 and > 200 against poliovirus type 1 and rhinovirus type 15, respectively. This compound was also active against other rhinovirus serotypes (2, 9, 14, 29, 39, 41, 59, 63, 70, 85, and 89) tested, having MIC50 values ranging from 0.016 to 0.5 μg/mL. Finally in contrast to quercetin it showed to be not mutagenic in concentrations up to 2.5 mg in the Ames test.
