330786-25-9

Basic information

• Product Name: PCI 29732
• Synonyms: PCI 29732;4-Amino-1-cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine;1-Cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• CAS NO: 330786-25-9
• Molecular Formula: C₂₂H₂₁N₅O
• Molecular Weight: 371.43504
• Mol File: 330786-25-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 599.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.36±0.1 g/cm3(Predicted)
• PKA: 4.24±0.30(Predicted)
• CAS DataBase Reference: PCI 29732(CAS DataBase Reference)
• NIST Chemistry Reference: PCI 29732(330786-25-9)
• EPA Substance Registry System: PCI 29732(330786-25-9)

Safety Data

• Hazardous Substances Data: 330786-25-9(Hazardous Substances Data)

Usage

General Description

PCI 29732 is a chemical compound that functions as an anti-inflammatory drug. Its primary use is in the treatment of inflammatory diseases like rheumatoid arthritis and lymphoma. The compound works by inhibiting the Bruton’s tyrosine kinase (BTK), an enzyme that plays a crucial role in the activation of pro-inflammatory cells. By blocking this enzyme, PCI 29732 effectively reduces inflammation and mitigates the symptoms of these diseases. It is currently undergoing clinical trials to further evaluate its therapeutic potential.

Upstream product

• 330786-24-8 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 96-41-3 Cyclopentanol