3316-42-5

Basic information

• Product Name: N-(2-hydroxy-1,2-diphenylethyl)-4-methylbenzenesulfonamide
• Synonyms: N-(2-hydroxy-1,2-diphenylethyl)-4-methylbenzenesulfonamide
• CAS NO: 3316-42-5
• Molecular Weight: 367.469
• Mol File: 3316-42-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: N-(2-hydroxy-1,2-diphenylethyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-hydroxy-1,2-diphenylethyl)-4-methylbenzenesulfonamide(3316-42-5)
• EPA Substance Registry System: N-(2-hydroxy-1,2-diphenylethyl)-4-methylbenzenesulfonamide(3316-42-5)

Safety Data

• Hazardous Substances Data: 3316-42-5(Hazardous Substances Data)

Upstream product

• 65996-43-2 N₁-(1-methyl-2-oxo-2-phenylethyl)-4-methyl-1-benzenesulfonamide 
• 885-75-6 2-amino-1,2-diphenyl-ethanone; hydrochloride 
• 32493-66-6 2-(2-oxo-1,2-diphenylethyl)isoindoline-1,3-dione 
• 1484-50-0 desyl bromide 
• 451-40-1 phenyl benzyl ketone 
• 588-59-0 stilbene 
• 127-65-1 chloroamine-T 
• 645-49-8 cis-stilben 
• 530-36-9 erythro-2-amino-1,2-diphenylethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 4746-86-5 hydroxy-diphenyl-acetaldehyde 
• 70-55-3 toluene-4-sulfonamide 
• 97305-99-2 N-(2,2-diphenylvinyl)-4-methylbenzenesulfonamide 
• 147054-74-8 N-(p-toluenesulfonyl)-2,3-diphenylaziridine 

Relevant articles and documents

Alkene Syn- And Anti-Oxyamination with Malonoyl Peroxides

Malonoyl peroxide 6 is an effective reagent for the syn- or anti-oxyamination of alkenes. Reaction of 6 and an alkene in the presence of O-tert-butyl-N-tosylcarbamate (R3 = CO2 tBu) leads to the anti-oxyaminated product in up to 99% yield. Use of O-methyl-N-tosyl carbamate (R3 = CO2Me) as the nitrogen nucleophile followed by treatment of the product with trifluoroacetic acid leads to the syn-oxyaminated product in up to 77% yield. Mechanisms consistent with the observed selectivities are proposed.

Pd(ii)-Catalyzed aerobic 1,2-difunctionalization of conjugated dienes: Efficient synthesis of morpholines and 2-morpholones

A novel and efficient methodology concerning the Pd(ii)-catalyzed intermolecular difunctionalization of conjugated dienes is reported to synthesize a series of functionalized morpholines and 2-morpholones. Widely distributed and easily obtained β-amino alcohols and α-amino acids, as starting nitrogen and oxygen sources, are successfully applied in the difunctionalization of conjugated dienes respectively. The majority of the desired products were obtained in moderate to excellent yields. Oxygen was successfully employed as a terminal oxidant. Further transformation of the generated products allowed for the expansion of structural diversity.

An iodine(iii) mediated oxidative rearrangement of enamines: efficient synthesis of α-amino ketones

An iodine(iii)-mediated, group-selective oxidative rearrangement of β,β-diarylenamines to α-amino ketones has been accomplished with excellent yield. The developed reaction involves the initial oxidation of enamine to an α-acyloxyimine intermediate and concomitant semipinacol rearrangement.