332-06-9

Basic information

• Product Name: 4-BROMOBUTYRONITRILE
• Synonyms: N,N'-Bis-(4-fluoro-phenyl)-hydrazine
• CAS NO: 332-06-9
• Molecular Formula: C₁₂H₁₀F₂N₂
• Molecular Weight: 220.22
• Mol File: 332-06-9.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-BROMOBUTYRONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMOBUTYRONITRILE(332-06-9)
• EPA Substance Registry System: 4-BROMOBUTYRONITRILE(332-06-9)

Safety Data

• Hazardous Substances Data: 332-06-9(Hazardous Substances Data)

Upstream product

• 332-07-0 bis-(4-fluorophenyl)diazene 
• 326-04-5 N,N'-Bis-(4-fluoro-phenyl)-diazene N-oxide 
• 332-07-0 (E)-bis(4-fluorophenyl)diazene 
• 371-40-4 4-fluoroaniline 
• 73183-34-3 bis(pinacol)diborane 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 332-07-0 (E)-bis(4-fluorophenyl)diazene 
• 137182-59-3 1-acetyl-1,2-bis(4-fluorophenyl)hydrazine 
• 137182-60-6 1,2-bis(4-fluorophenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one 
• 332-07-0 bis-(4-fluorophenyl)diazene 
• 16858-27-8 1,2-bis-(4-fluoro-phenyl)-pyrazolidine-3,5-dione 
• 326-04-5 1,2-bis(4-fluorophenyl)diazene oxide 
• 371-40-4 4-fluoroaniline 

Relevant articles and documents

Chemoselective electrochemical reduction of nitroarenes with gaseous ammonia

Valuable aromatic nitrogen compounds can be synthesized by reduction of nitroarenes. Herein, we report electrochemical reduction of nitroarenes by a protocol that uses inert graphite felt as electrodes and ammonia as a reductant. Depending on the cell voltage and the solvent, the protocol can be used to obtain aromatic azoxy, azo, and hydrazo compounds, as well as aniline derivatives with high chemoselectivities. The protocol can be readily scaled up to >10 g with no decrease in yield, demonstrating its potential synthetic utility. A stepwise cathodic reduction pathway was proposed to account for the generations of products in turn.

Convenient semihydrogenation of azoarenes to hydrazoarenes using H2

The high atom-economical and eco-benign nature of hydrogenation reactions make them much more superior to conventional reduction and transfer hydrogenation. Herein, a convenient and highly selective hydrogenation reaction of azoarenes using molecular hydrogen to access diverse hydrazoarenes is reported. The present catalytic method is general and operationally simple, and it operates under exceedingly mild conditions (room temperature and 1 atm of hydrogen pressure). The reusability of catalysts used in this method is also successfully demonstrated.

Method for preparing 4, 4'-disubstituted-2, 2'-diaminodiphenyl and hydrochloride thereof through reductive coupling

The invention discloses a method for preparing 4, 4'-disubstituted-2, 2'-diaminodiphenyl and hydrochloride thereof based on 4-substituted nitrobenzene and through reductive coupling. The method comprises the following steps: in the presence of an organic