332023-12-8

Basic information

• Product Name: 1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE
• Synonyms: TIMTEC-BB SBB009826;BUTTPARK 83\09-96;ASISCHEM P08669;ART-CHEM-BB B025587;AKOS BB-8576;1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE;ZERENEX ZX003800;1-(2-chloro-6-nitrophenyl)piperazine(SALTDATA: FREE)
• CAS NO: 332023-12-8
• Molecular Formula: C₁₀H₁₂ClN₃O₂
• Molecular Weight: 241.67
• Mol File: 332023-12-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 95-97
• Boiling Point: 384.3°C at 760 mmHg
• Flash Point: 186.2°C
• Appearance: /Solid
• Density: 1.331g/cm³
• Vapor Pressure: 4.14E-06mmHg at 25°C
• Refractive Index: 1.589
• PKA: 8.60±0.10(Predicted)
• CAS DataBase Reference: 1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE(332023-12-8)
• EPA Substance Registry System: 1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE(332023-12-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 332023-12-8(Hazardous Substances Data)

Usage

General Description

1-(2-chloro-6-nitrophenyl)piperazine is a chemical compound with a molecular formula C10H13ClN4O2. It is a piperazine derivative with a chloro and nitro group attached to the benzene ring. 1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. It has potential applications in the development of psychiatric medications as it is known to have affinity for certain neurotransmitter receptors in the brain. Additionally, it is also used in the research and development of new drugs for treating neurological disorders and mental health conditions. Its chemical properties and structural features make it an important building block for the synthesis of a wide range of biologically active compounds.

InChI:InChI=1/C10H12ClN3O2/c11-8-2-1-3-9(14(15)16)10(8)13-6-4-12-5-7-13/h1-3,12H,4-7H2

Upstream product

• 400803-05-6 4-(2-chloro-6-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 110-85-0 piperazine 
• 3209-22-1 1,2-Dichloro-3-nitrobenzene 

Downstream Products

• 400803-06-7 1-{3-[4-(2-chloro-6-nitro-phenyl)-piperazin-1-yl]-propyl}-5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine 
• 400803-05-6 4-(2-chloro-6-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 400802-70-2 3-chloro-2-(4-{3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperazin-1-yl)-phenylamine 
• 400802-58-6 1-[3-chloro-2-(4-{3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperazin-1-yl)-phenyl]-urea 

Relevant articles and documents

Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors

A novel series of c-jun N-terminal kinase (JNK) inhibitors were designed and developed from a high-throughput-screening hit. Through the optimization of the piperazine amide 1, several potent compounds were discovered. The X-ray crystal structure of 4g sh

Method for treating allergies using substituted pyrazoles

A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.