400803-05-6

Basic information

• Product Name: 1-Piperazinecarboxylic acid, 4-(2-chloro-6-nitrophenyl)-, 1,1-dimethylethyl ester
• CAS NO: 400803-05-6
• Molecular Formula: C15H20ClN3O4
• Molecular Weight: 341.794
• Mol File: 400803-05-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Piperazinecarboxylic acid, 4-(2-chloro-6-nitrophenyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinecarboxylic acid, 4-(2-chloro-6-nitrophenyl)-, 1,1-dimethylethyl ester(400803-05-6)
• EPA Substance Registry System: 1-Piperazinecarboxylic acid, 4-(2-chloro-6-nitrophenyl)-, 1,1-dimethylethyl ester(400803-05-6)

Safety Data

• Hazardous Substances Data: 400803-05-6(Hazardous Substances Data)

Upstream product

• 332023-12-8 1-(2-chloro-6-nitro-phenyl)-piperazine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 400802-60-0 N-[3-chloro-2-(4-{2-hydroxy-3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperazin-1-yl)-phenyl]-methanesulfonamide 
• 400802-58-6 1-[3-chloro-2-(4-{3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperazin-1-yl)-phenyl]-urea 
• 400803-06-7 1-{3-[4-(2-chloro-6-nitro-phenyl)-piperazin-1-yl]-propyl}-5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine 
• 400802-70-2 3-chloro-2-(4-{3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperazin-1-yl)-phenylamine 
• 400803-12-5 4-(2-chloro-6-methanesulfonylamino-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 332023-12-8 1-(2-chloro-6-nitro-phenyl)-piperazine 

Relevant articles and documents

Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors

A novel series of c-jun N-terminal kinase (JNK) inhibitors were designed and developed from a high-throughput-screening hit. Through the optimization of the piperazine amide 1, several potent compounds were discovered. The X-ray crystal structure of 4g sh