333333-34-9

Basic information

• Product Name: 1,3-dihydro-1-oxo-5-Isobenzofurancarboxaldehyde
• Synonyms: 1,3-dihydro-1-oxo-5-Isobenzofurancarboxaldehyde;1-Oxo-1,3-dihydroisobenzofuran-5-carbaldehyde
• CAS NO: 333333-34-9
• Molecular Formula: C₉H₆O₃
• Molecular Weight: 162.14214
• Mol File: 333333-34-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1,3-dihydro-1-oxo-5-Isobenzofurancarboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dihydro-1-oxo-5-Isobenzofurancarboxaldehyde(333333-34-9)
• EPA Substance Registry System: 1,3-dihydro-1-oxo-5-Isobenzofurancarboxaldehyde(333333-34-9)

Safety Data

• Hazardous Substances Data: 333333-34-9(Hazardous Substances Data)

Usage

General Description

1,3-dihydro-1-oxo-5-Isobenzofurancarboxaldehyde, also known as isobenzofuran-1,3-dione, is a chemical compound with the molecular formula C9H6O3. It is a yellow-colored solid with a floral odor, and it is commonly used in the production of fragrances and flavorings. It is also utilized as an intermediate in the manufacturing of pharmaceuticals and agrochemicals. 1,3-dihydro-1-oxo-5-Isobenzofurancarboxaldehyde is known to be stable under normal temperature and pressure, but it may react violently with strong oxidizing agents and reducing agents. Additionally, it may decompose in the presence of strong acids and bases. Overall, 1,3-dihydro-1-oxo-5-Isobenzofurancarboxaldehyde has various industrial applications due to its aromatic properties and chemical reactivity.

Upstream product

• 7732-18-5 water 
• 108-38-3 m-xylene 
• 21900-42-5 2,4-dimethylbenzoyl chloride 
• 89-74-7 2,4-dimethylacetophenone. 
• 611-01-8 2,4-dimethyl-benzoic acid 
• 65006-89-5 5-(hydroxymethyl)isobenzofuran-1(3H)-one 
• 227954-90-7 (1-oxo-1,3-dihydroisobenzofuran-5-yl)carbonyl chloride 
• 4792-29-4 5-carboxyphtalide 
• 64169-34-2 5-bromophthalide 
• 20461-86-3 2,2-diethoxy acetic acid 
• 876156-35-3 5-ethenyl-2-benzofuran-1(3H)-one 

Downstream Products

• 23405-34-7 hydroxymethyl-terephthalic acid 

Relevant articles and documents

SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS

Disclosed are compounds of Formula (I), or a salt thereof, wherein: X is CR4 or N; Y is CR4 or N, provided that Y is N only if X is N; R1 is Formulae (A) or (B); each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, R3, R4, L1, R1a, R1b, R1c, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.

Inhibition of the pore-forming protein perforin by a series of aryl-substituted isobenzofuran-1(3H)-ones

An aryl-substituted isobenzofuran-1(3H)-one lead compound was identified from a high throughput screen designed to find inhibitors of the lymphocyte pore-forming protein perforin. A series of analogs were then designed and prepared, exploring structure-ac

Process for the preparation of 5-subtituted isobenzofurans

There is described a process for the preparation of citalopram and of its pharmaceutically acceptable salts, which comprises treating a 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbaldoxime, O-substituted preferably with a diphenylmethyl or triphenylmethyl group, with formic-acetic anhydride. Furthermore, the total synthesis of citalopram, as free base or in form of its pharmaceutically acceptable salt, starting from 5-formylphthalide is described.