334-56-5Relevant articles and documents
DARSTELLUNG VON PRIMAEREN ALKYLFLUORIDEN UNTER EINSATZ DER PHASEN TRANSFER KATALYSE
Dermiek, Salman,Sasson, Yoel
, p. 431 - 438 (1983)
The influence of the following factors on the solid-liquid PTC fluorination reaction of primary alkyl halides was studied: the catalyst quantity applied, the water content of solid alkali fluoride salt, and the type of catalyst.Kinetic curves at different temperatures were found for the reaction.The maximum yield is a function of the interaction of two parallel running reactions, namely the direct fluorination reaction and the catalyst decomposition.
Synthesis, Characterization, and Reactivity of Thermally Stable Anhydrous Quaternary Ammonium Fluorides
Elias, Shlomi,Karton-Lifshin, Naama,Yehezkel, Lea,Ashkenazi, Nissan,Columbus, Ishay,Zafrani, Yossi
supporting information, p. 3039 - 3042 (2017/06/23)
The synthesis and properties of a new class of anhydrous quaternary ammonium fluorides, based on the rigid skeleton azabicyclo[2.2.2]octane, is described. Compounds 2a-d were easily prepared by passing the corresponding ammonium iodides over fluoride-based resin followed by drying their hydrated form at 100 or 140 °C under reduced pressure. The stability (experimental and theoretical study), solubility, reactivity, and characterization by solution and solid-state MAS NMR are discussed.
Selective mono-acylation of 1,2- and 1,3-diols using (α,α- difluoroalkyl)amines
Wakita, Natsumi,Hara, Shoji
scheme or table, p. 7939 - 7945 (2010/10/19)
In the reaction of N,N-diethyl-α,α-difluorobenzylamine (DFBA) with 1,2- or 1,3-diols, selective mono-benzoylation occurs to afford mono-esters of the diols in good yield. The reaction is completed under mild conditions in a short reaction time. Further, prim-, sec-, and tert-diols and catechol can be converted to the corresponding mono-benzoates. DFBA is used for the protection of the hydroxy group in sugars. The selective mono-nicotinylation, formylation and pivaloylation of diols are also performed by using the corresponding difluoroalkylamines.