33421-53-3

Basic information

• Product Name: 2,3-DIPHENYLPYRIDINE
• Synonyms: RARECHEM AQ NN 0177;2,3-DIPHENYLPYRIDINE
• CAS NO: 33421-53-3
• Molecular Formula: C₁₇H₁₃N
• Molecular Weight: 231.29
• EINECS: 251-511-2
• Mol File: 33421-53-3.mol
• Article Data: 9

Chemical Properties

• Melting Point: 54-57 °C
• Boiling Point: 348.1 °C at 760 mmHg
• Flash Point: 149 °C
• Appearance: /
• Density: 1.084 g/cm³
• Vapor Pressure: 0.000103mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: 2-8°C
• PKA: 4.06±0.10(Predicted)
• CAS DataBase Reference: 2,3-DIPHENYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIPHENYLPYRIDINE(33421-53-3)
• EPA Substance Registry System: 2,3-DIPHENYLPYRIDINE(33421-53-3)

Safety Data

• Hazardous Substances Data: 33421-53-3(Hazardous Substances Data)

Usage

General Description

2,3-Diphenylpyridine is a chemical compound with the molecular formula C17H13N. It belongs to the class of organic compounds known as diphenylpyridines, which are aromatic heterocyclic compounds containing a pyridine ring substituted with two phenyl groups. 2,3-DIPHENYLPYRIDINE is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a ligand in coordination chemistry to form metal complexes. 2,3-Diphenylpyridine is a yellowish crystalline solid with a melting point of 168-170°C and it is sparingly soluble in water but soluble in organic solvents. Due to its versatile applications, it is an important intermediate in the chemical industry.

InChI:InChI=1/C17H13N/c1-3-8-14(9-4-1)16-12-7-13-18-17(16)15-10-5-2-6-11-15/h1-13H

Upstream product

• 70336-73-1 2,7-diphenyl-[1,3]oxazepine 
• 87058-40-0 1,2-Diphenyl-1,5-pentandion 
• 731-65-7 cis-2,3-Dihydro-2,3-diphenyl-1H-1,4-diazepine 
• 134-81-6 benzil 
• 451-40-1 phenyl benzyl ketone 
• 2402-77-9 2,3-dichloro-pyridine 
• 100-58-3 phenylmagnesium bromide 
• 109-76-2 Trimethylenediamine 
• 156-87-6 propan-1-ol-3-amine 
• 2450-71-7 Propargylamine 

Downstream Products

• 475086-46-5 2,3-diphenylpyridin-1-oxide 

Relevant articles and documents

Iridium-catalyzed annulation between 1,2-diarylethanone and 3-aminopropanol toward site-specific 2,3-diaryl pyridines

An iridium-catalyzed annulation between 1,2-diarylethanone and 3-aminopropanol was developed, leading to site specific 2,3-diarylpyridines in moderate yields. 3-Aminopropanol served as both a four-atom component and solvent during this procedure, releasing water as a clean by-product. The reaction may proceed with sequential imine formation, alcohol oxidation and intramolecular cyclization by Knoevenagel reaction.

Application of Cu-MOF (Metal Organic Framework) type catalyst in preparing polysubstitution pyridine derivative

The invention discloses application of Cu-MOF (Metal Organic Framework) type catalyst in preparing polysubstitution pyridine derivative. The method for carrying out catalytic preparation on the polysubstitution pyridine derivative by the Cu-MOF type catalyst comprises the following steps: carrying out cyclization reaction on an even mixing system which contains the Cu-MOF type catalyst, carbonyl compound, propargylamine and solvent at the temperature of room temperature to 100 DEG C to obtain the polysubstitution pyridine derivative. According to the method, the amination/cyclization/arylatingreaction of the catalyzing carbonylation compound of the Cu-MOF type catalyst and propargylamine can be realized for the first time, and various polysubstitution pyridine derivatives can be obtainedat a high yield. The Cu-MOF type catalyst used by the invention is heterogeneous catalyst which is stable for air and water, environment pollution is reduced, the Cu-MOF type catalyst does not need tobe protected by inert gas, a synthesis method is simple, raw material price is low, and the Cu-MOF type catalyst can be reused. Meanwhile, the Cu-MOF type catalyst has the advantages of low reactiontemperature, high reaction selectivity, high efficiency and wide applicable range of substrate.

Biphenyl-based diaminophosphine oxides as air-stable preligands for the nickel-catalyzed kumada-tamao-corriu coupling of deactivated aryl chlorides, fluorides, and tosylates

A cooperative couple: Cooperative bimetallic activation of C-F and C-O bonds gave rise to easy coupling with aryl fluorides and tosylates. Novel air- and moisture-stable diaminophosphine oxides derived from 1,1′-biphenyl-2, 2′-diamine proved to be versatile preligands for the nickel-catalyzed cross-coupling of aryl Grignard reagents with a variety of deactivated aryl chlorides, fluorides, and tosylates (see scheme). Copyright