33490-49-2Relevant articles and documents
Highly efficient cyanoimidation of aldehydes
Yin, Ping,Wen-Bo, Ma.,Chen, Yue,Huang, Wen-Cal,Deng, Yong,He, Ling
supporting information; experimental part, p. 5482 - 5485 (2010/02/27)
"Chemical Equation Presented" Cyanoimidation of aldehydes using cyanamide as a nitrogen source and using NBS as an oxidant was achieved in high yields without the addition of a catalyst. The method has several advantages, Including mild conditions, simple workflow, and inexpensive reagents. The reaction proceeds in a one-pot manner, giving rise to the formation of intermolecular C-N and C-O bonds. Subsequently, the substituted W-cyanobenimidate products may also undergo a cyclization reaction to give 1,2,4-triazole derivatives in high yields.
Adenosine receptor ligands and their use in the treatment of disease
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, (2008/06/13)
The invention relates to cyclic heteroaromatic compounds, containing at least one nitrogen atom, and to their use in the manufacture of medicaments for the treatment of diseases, related to adenosine receptor modulators, such as Alzheimer's disease, Parkinson's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, asthma, allergic responses, hypoxia, ischaemia, seizure, substance abuse, sedation and they may be active as muscle relaxants, antipsychotics, anti epileptics, anticonvulsants and cardiaprotective agents.