33493-31-1Relevant articles and documents
Geminal difunctionalization of α-diazo arylmethylphosphonates: Synthesis of fluorinated phosphonates
Zhou, Yujing,Zhang, Yan,Wang, Jianbo
, p. 10444 - 10453 (2016/11/18)
A general approach towards diverse fluorinated phosphonates via geminal difunctionalization reactions of α-diazo arylmethylphosphonates is described. The diazo functionality (RR′CN2) is successfully converted to RR′CF2, RR′CHF, RR′CFBr or RR′CFNR′′2 groups by employing different fluorination reagents. A variety of fluorinated organophosphorus compounds were readily accessed in good to excellent yields from a common type of precursor.
A new and direct approach to functionalized biaryl α-ketophosphonic acids via aqueous Suzuki coupling on solid support
Li, Xianfeng,Szardenings, Anna Katrin,Holmes, Christopher P.,Wang, Liang,Bhandari, Ashok,Shi, Lihong,Navre, Marc,Jang, Larry,Grove, J. Russell
, p. 19 - 22 (2007/10/03)
A new method for the synthesis of functionalized biaryl α-ketophosphonic acids has been developed. The key step involves the use of sodium bromobenzoyl phosphonates to react with polymer-bound boronic acids via microwave-assisted aqueous Suzuki coupling. This approach provides rapid access to a wide range of diverse biaryl analogues containing an α-ketophosphonic acid moiety.
One-pot synthesis of 1-hydroxymethylene-1,1-bisphosphonate partial esters
Migianu, Evelyne,Mallard, Isabelle,Bouchemal, Nadia,Lecouvey, Marc
, p. 4511 - 4513 (2007/10/03)
A selective one-pot procedure of synthesis of 1-hydroxymethylene-1,1- bisphosphonic partial trimethylesters and P,P-, P,P′-diesters was described.
