336804-78-5Relevant articles and documents
An efficient acylation/base-catalyzed cyclization of thioureas affords N,N′-disubstituted thiobarbituric acids
Heath, Perry C.,Huang, Charles Q.,Lowe, Richard F.,McCarthy, James R.,Weigel, Leland O.,Whitten, Jeffery P.
, p. 1607 - 1610 (2007/10/03)
Acylation of 1,3-disubstituted thioureas with methyl malonyl chloride followed by base-catalyzed cyclization leads to the preparation of 1,3-disubstituted-2-thiobarbituric acids in high yield.