337-53-1Relevant articles and documents
Difluromethylphosphonium salt, and preparation method and application thereof
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Paragraph 0220; 0221; 0222; 0223, (2017/08/02)
The invention discloses difluromethylphosphonium salt, and a preparation method and application thereof. A synthetic method of the difluromethylphosphonium salt disclosed by the invention comprises the following steps of in a solvent, carrying out a react
Rh-Catalyzed arylation of fluorinated ketones with arylboronic acids
Dobson, Luca S.,Pattison, Graham
supporting information, p. 11116 - 11119 (2016/09/19)
The Rh-catalyzed arylation of fluorinated ketones with boronic acids is reported. This efficient process allows access to fluorinated alcohols in high yields under mild conditions. Competition experiments suggest that difluoromethyl ketones are more reactive than trifluoromethyl ketones in this process, despite their decreased electronic activation, an effect we postulate to be steric in origin.
Nucleophilic difluoromethylation and difluoromethylenation of aldehydes and ketones using diethyl difluoromethylphosphonate
Beier, Petr,Alexandrova, Anastasia V.,Zibinsky, Mikhail,Surya Prakash
experimental part, p. 10977 - 10985 (2009/04/11)
New methodology for difluoromethylation and difluoromethylenation of aldehydes and ketones based on nucleophilic fluorination using diethyl difluoromethylphosphonate (1) was developed.