337-72-4

Basic information

• Product Name: Benzenemethanol, a-(fluoromethyl)-a-phenyl-
• CAS NO: 337-72-4
• Molecular Formula: C14H13FO
• Molecular Weight: 216.255
• Mol File: 337-72-4.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-(fluoromethyl)-a-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-(fluoromethyl)-a-phenyl-(337-72-4)
• EPA Substance Registry System: Benzenemethanol, a-(fluoromethyl)-a-phenyl-(337-72-4)

Safety Data

• Hazardous Substances Data: 337-72-4(Hazardous Substances Data)

Upstream product

• 60-29-7 diethyl ether 
• 453-18-9 methyl fluoroacetate 
• 459-72-3 ethyl 2-fluoroacetate 
• 118268-22-7 C₂₁H₂₀FNO₂S 
• 530-48-3 1,1-Diphenylethylene 
• 119-61-9 benzophenone 
• 373-53-5 fluoroiodomethane 
• 65325-68-0 1-(monofluoromethyl sulfinyl)benzene 
• 591-51-5 phenyllithium 
• 21369-64-2 n-hexyllithium 
• 70-11-1 α-bromoacetophenone 
• 450-95-3 2-fluoroacetophenone 
• 98-80-6 phenylboronic acid 
• 67-56-1 methanol 

Downstream Products

• 390-75-0 2-fluoro-1,1-diphenylethene 
• 466-35-3 2-fluoro-1-fluoromethyl-1,3,3-triphenyl-indan 
• 36586-15-9 (2-ethoxyethene-1,1-diyl)dibenzene 
• 379-83-9 1,2-Difluoro-1,1-diphenylethane 
• 130728-72-2 4-phenyl-1,2-naphthalenedicarboxylic anhydride 

Relevant articles and documents

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Rh-Catalyzed arylation of fluorinated ketones with arylboronic acids

The Rh-catalyzed arylation of fluorinated ketones with boronic acids is reported. This efficient process allows access to fluorinated alcohols in high yields under mild conditions. Competition experiments suggest that difluoromethyl ketones are more reactive than trifluoromethyl ketones in this process, despite their decreased electronic activation, an effect we postulate to be steric in origin.

Transformations of organic molecules with F-TEDA-BF4 in ionic liquid media

The transformations of organic molecules with F-TEDA-BF4 (1) were investigated in the hydrophilic ionic liquid (IL) 1-butyl-3-methyl- imidazolium tetrafluoroborate ([bmim][BF4], 2) and the hydrophobic IL 1-butyl-3-methyl-imidazolium hexafluorophosphate ([bmim][PF6], 3). The range of substrates included alkyl substituted phenols 4a-c, 9, 13, 1,1-diphenylethene (15), alkyl aryl ketones 19-22, aldehydes 23-25 and methoxy-substituted benzene derivatives 26-30. The evaluation of the outcome of reactions performed in IL media in comparison to those of the corresponding reactions in conventional organic solvents revealed that the transformations in IL are less efficient and selective. The effect of the presence of a nucleophile (MeOH, H2O, MeCN) on the course of reaction was also studied.