339-25-3

Basic information

• Product Name: P-FLUOROPHENYL-P-METHOXYPHENYL SULFONE
• Synonyms: P-FLUOROPHENYL-P-METHOXYPHENYL SULFONE;4-FLUOROPHENYL 4-METHOXYPHENYL SULFONE;1-(4-fluorophenyl)sulfonyl-4-methoxybenzene
• CAS NO: 339-25-3
• Molecular Formula: C₁₃H₁₁FO₃S
• Molecular Weight: 266.29
• Mol File: 339-25-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 407.5°Cat760mmHg
• Flash Point: 200.2°C
• Appearance: /
• Density: 1.292g/cm³
• Vapor Pressure: 1.77E-06mmHg at 25°C
• Refractive Index: 1.561
• CAS DataBase Reference: P-FLUOROPHENYL-P-METHOXYPHENYL SULFONE(CAS DataBase Reference)
• NIST Chemistry Reference: P-FLUOROPHENYL-P-METHOXYPHENYL SULFONE(339-25-3)
• EPA Substance Registry System: P-FLUOROPHENYL-P-METHOXYPHENYL SULFONE(339-25-3)

Safety Data

• Hazardous Substances Data: 339-25-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H11FO3S/c1-17-11-4-8-13(9-5-11)18(15,16)12-6-2-10(14)3-7-12/h2-9H,1H3

Upstream product

• 383-29-9 bis(p-fluorophenyl)sulfone 
• 917-58-8 potassium ethoxide 
• 349-88-2 4-Fluorobenzenesulfonyl chloride 
• 100-66-3 methoxybenzene 
• 462-06-6 fluorobenzene 
• 371-42-6 4-Fluorothiophenol 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 696-62-8 para-iodoanisole 
• 824-80-6 sodium 4-fluorobenzenesulfinate 
• 732306-64-8 bis(4-fluorophenyl)iodonium triflate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 312-36-7 4-fluoro-4'-hydroxydiphenyl sulfone 
• 74-88-4 methyl iodide 
• 2266-41-3 4-fluorobenzenesulfonylhydrazide 

Downstream Products

• 312-36-7 4-fluoro-4'-hydroxydiphenyl sulfone 

Relevant articles and documents

Indium(III)-catalysed aryl sulfonylation reactions

A rapid, high yielding and regioselective process has been developed for the synthesis of biaryl sulfones via sulfonylation reactions catalysed by indium(III) chloride.

Pd/NHC-catalyzed arylsulfonylation of boronic acids: A general and direct protocol to access diarylsulfones

For the first time, robust NHC-Pd complexes have been demonstrated as highly efficient catalysts in the direct arylsulfonylation of boronic acids. Remarkably, a broad number of diaryliodonium salts as powerful electrophilic arylation reagents are well compatible to form functional ortho-substituted diarylsulfones in satisfactory yields. Owing to the stronger σ-donor and weaker π-acceptor properties, the acenaphthoimidazolylidene ligands exhibit higher catalytic activities towards this challenging one-step arylsulfonylation reaction.

Organic photoredox catalysis enabled cross-coupling of arenediazonium and sulfinate salts: Synthesis of (un)symmetrical diaryl/alkyl aryl sulfones

We disclose herein the first transition-metal-and external oxidant/reductant-free visible-light-mediated synthesis of (un)symmetrical diaryl/alkyl aryl sulfones from arenediazonium tetrafluoroborates and sodium sulfinates using eosin Y as an organic photoredox catalyst. The utilization of visible light as an inexpensive and ecosustainable energy source, operational simplicity, ambient temperature and clean reaction in aqueous acetonitrile are the salient features of the developed protocol. The desired sulfones were also synthesized via a one-pot, two-step process directly from anilines and sulfinate salts in good to excellent yields.