3392-15-2Relevant articles and documents
Practical Peptide Synthesis Mediated by a Recyclable Hypervalent Iodine Reagent and Tris(4-methoxyphenyl)phosphine
Zhang, Chi,Liu, Shan-Shan,Sun, Bo,Tian, Jun
supporting information, p. 4106 - 4109 (2015/09/01)
6-(3,5-Bis(trifluoromethyl)phenyl)-1H,4H-2aλ3-ioda-2,3-dioxacyclopenta[hi]indene-1,4-dione (p-BTFP-iodosodilactone, 1a) was synthesized and demonstrated to be an efficient hypervalent iodine(III) reagent for the synthesis of dipeptides from various standard amino acids, including sterically hindered amino acids, in good to high yields within 30 min in the presence of tris(4-methoxyphenyl)phosphine. In addition, the combined system of 1a/(4-MeOC6H4)3P was used to synthesize the pentapeptide leu-enkephalin in protected form. It is worth noting that 1a can be regenerated readily after reaction.
Discovery of potent and selective phenylalanine derived CCR3 antagonists. Part 1
Dhanak, Dashyant,Christmann, Lisa T.,Darcy, Michael G.,Jurewicz, Anthony J.,Keenan, Richard M.,Lee, Judithann,Sarau, Henry M.,Widdowson, Katherine L.,White, John R.
, p. 1441 - 1444 (2007/10/03)
The discovery of a series of phenylalanine derived CCR3 antagonists is reported. Parallel, solution-phase library synthesis has been utilized to delineate the structure-activity relationship leading to the synthesis of highly potent, CCR3-selective antagonists.
A novel support for enzyme adsorption: Properties and applications of aerogels in low water media
Basso,De Martin,Ebert,Gardossi,Tomat,Casarci,Li Rosi
, p. 8627 - 8630 (2007/10/03)
Aerogels, because of their porosity, have a great ability to adsorb water, and this characteristic was exploited to extend the applicability of aerogels for the adsorption and entrapment of hydrolases to be used in organic media. The applicability of aero
