339267-24-2Relevant articles and documents
Synthesis of trisphaeridine and norchelerythrine through palladium-catalyzed aryl-aryl coupling reactions
Harayama, Takashi,Akamatsu, Hisashi,Okamura, Kana,Miyagoe, Taeko,Akiyama, Toshihiko,Abe, Hitoshi,Takeuchi, Yasuo
, p. 523 - 528 (2007/10/03)
The synthesis of triphaeridine and norchelerythrine through palladium-catalyzed aryl-aryl coupling reactions was studied. The secondary amides were synthesized from 6-bromopiperonylicacid and aniline, and from piperonylic acid and 2-iodoaniline respectively, and were methoxymethylated for the preparation of starting materials for the cyclization reaction. All experiments were carried out in an argon atmosphere and the extract was washed with brine. The nuclear magnetic resonance (NMR) spectral data showed the presence of singlet signals due to aromatic proton in the products.