34097-18-2Relevant articles and documents
Fused pyrimidines. 7. Nucleosides of pyrimidopyrimidinediones and pteridinediones as potential chemotherapeutic agents
Nagarajan,Meltsner, Bernard R.,Delia, Thomas J.
, p. 1581 - 1585 (1997)
Several nucleoside derivatives of pyrimido [4,5-d]pyrimidine-2,4(1H,3H)- dione 1 and 2,4(1H,3H)-pteridinedione 2 were prepared. Treating the appropriate silylated nucleobase with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D- ribofuranose 3 in the presence of trimet
Nucleoside Syntheses, XXII. Nucleoside Synthesis with Trimethylsilyl Triflate and Perchlorate as Catalysts
Vorbrueggen, Helmut,Krolikiewicz, Konrad,Bennua, Baerbel
, p. 1234 - 1255 (2007/10/02)
The novel Lewis acids (CH3)3SiOSO2CF3 (5), (CH3)3SiOSO2C4F9 (6), and (CH3)3SiClO4 (4) are highly selective and efficient Friedel-Crafts catalysts for nucleoside formation from silylated heterocycles and peracylated sugars as well as for rearrangements of persilylated protected nucleosides.With basic silylated heterocycles these new catalysts give much higher yields of the natural N-1-nucleosides than with SnCl4.